Fmoc-Cys(Boc-methyl)-OH
Fmoc-Cys(Boc-methyl)-OH (CAS: 269730-62-3), a protected cysteine derivative with empirical formula C24H27NO6S and a molecular weight of 457.54 g/mol, is a vital building block in chemical synthesis. It plays a significant role in peptide chemistry and the development of unnatural amino acid derivatives. This compound is essential for researchers involved in chemical biology and custom synthesis requiring precise control over amino acid modification.
- IUPAC
- (R)-Fmoc-2-amino-3-(tert-butoxycarbonylmethylsulfanyl)-propionic acid,Fmoc-Cys(t-butylcarboxymethyl)-OH,Fmoc-Cys(tert-butoxycarbonylmethyl)-OH
- Synonyms
- (R)-Fmoc-2-amino-3-(tert-butoxycarbonylmethylsulfanyl)-propionic acidFmoc-Cys(t-butylcarboxymethyl)-OHFmoc-Cys(tert-butoxycarbonylmethyl)-OH
Peptide Synthesis
Fmoc-Cys(Boc-methyl)-OH is employed as a protected amino acid in solid-phase and solution-phase peptide synthesis. The Boc-methyl protecting group on the cysteine side chain allows for selective deprotection during peptide chain elongation.
Chemical Biology Research
This derivative is utilized in chemical biology for the construction of peptides and peptidomimetics with modified cysteine residues. It facilitates studies involving protein structure, function, and interaction.
Custom Synthesis of Biomolecules
Researchers and chemists use Fmoc-Cys(Boc-methyl)-OH in the custom synthesis of complex peptides, cyclic peptides, and other biomolecules where controlled incorporation of a modified cysteine is required.
Development of Unnatural Amino Acid Derivatives
The compound serves as a precursor or intermediate in the synthesis of novel unnatural amino acid derivatives, expanding the toolkit for protein engineering and drug discovery.
| Molecular weight | 457.54 |
|---|---|
| Empirical formula | C24H27NO6S |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]/D -48.0±2.0°, c = 1 in DMF |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Cys(Boc-methyl)-OH used for?
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Fmoc-Cys(Boc-methyl)-OH is primarily used in peptide synthesis, chemical biology research, and the custom synthesis of biomolecules requiring modified cysteine residues. It is a key building block for unnatural amino acid derivatives.
What are the CAS number and formula for Fmoc-Cys(Boc-methyl)-OH?
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The CAS number for Fmoc-Cys(Boc-methyl)-OH is 269730-62-3, and its empirical formula is C24H27NO6S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Cys(Boc-methyl)-OH with an assay of ≥98.0% determined by HPLC. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-Cys(Boc-methyl)-OH be handled and stored?
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Handle Fmoc-Cys(Boc-methyl)-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the product at 2-8°C.
Is Fmoc-Cys(Boc-methyl)-OH a controlled substance?
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There is no indication in the provided data that Fmoc-Cys(Boc-methyl)-OH is a controlled substance.
How is Fmoc-Cys(Boc-methyl)-OH packed and shipped?
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Products are carefully packed according to industry standards to ensure integrity during transit and are exported globally by Tech Serve Solutions.
How can I request a quote or sample for Fmoc-Cys(Boc-methyl)-OH?
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To request a quote or sample, please contact our sales team through the designated channels on the Tech Serve Solutions website.
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