Fmoc-Cys(4-methoxytrityl)-OH
Fmoc-Cys(4-methoxytrityl)-OH, CAS 177582-21-7, is a protected cysteine derivative with the empirical formula C38H33NO5S and a molecular weight of 615.74 g/mol. This compound features the Fmoc protecting group on the amine and a 4-methoxytrityl (Mmt) group on the cysteine side chain thiol. It is primarily utilised in solid-phase peptide synthesis (SPPS) and related biochemical research requiring controlled peptide assembly.
- IUPAC
- (R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[(4-methoxyphenyl)diphenylmethylsulfanyl]propionic acid,Fmoc-Cys(Mmt)-OH,Nα-(9-Fluorenylmethyloxycarbonyl)-S-4-methoxytrityl-L-cysteine
- Synonyms
- Fmoc-Cys(Mmt)-OHNα-(9-Fluorenylmethyloxycarbonyl)-S-4-methoxytrityl-L-cysteine(R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[(4-methoxyphenyl)diphenylmethylsulfanyl]propionic acid
Solid-Phase Peptide Synthesis (SPPS)
Fmoc-Cys(4-methoxytrityl)-OH serves as a crucial building block in SPPS. The Mmt protecting group allows for selective deprotection under mild acidic conditions, facilitating controlled chain elongation.
Peptide Chemistry
This derivative is instrumental in synthesising peptides containing cysteine residues. Its protected thiol prevents unwanted side reactions during coupling steps, ensuring the integrity of the final peptide sequence.
Chemical Biology Research
Researchers utilise Fmoc-Cys(4-methoxytrityl)-OH to construct complex peptides for studying biological processes, protein interactions, and developing peptide-based therapeutics.
Custom Peptide Synthesis
It is a valuable reagent for custom synthesis laboratories requiring high-purity amino acid derivatives for bespoke peptide production.
| Molecular weight | 615.74 |
|---|---|
| Empirical formula | C38H33NO5S |
| Assay | ≥98% (HPLC) |
| Optical activity | [α]/D +14.0±1.0°, c = 1 in THF |
| Storage temperature | 2-8°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Cys(4-methoxytrityl)-OH used for?
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Fmoc-Cys(4-methoxytrityl)-OH is primarily used as a building block in solid-phase peptide synthesis (SPPS) and peptide chemistry, particularly for constructing peptides containing cysteine residues where selective protection and deprotection of the thiol group are required.
What is the CAS number and formula for Fmoc-Cys(4-methoxytrityl)-OH?
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The CAS number for Fmoc-Cys(4-methoxytrityl)-OH is 177582-21-7, and its empirical formula is C38H33NO5S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Cys(4-methoxytrityl)-OH with an assay of ≥98% (HPLC). This product is intended for research and synthesis purposes and is not represented as USP, BP, or EP grade.
How should Fmoc-Cys(4-methoxytrityl)-OH be handled and stored?
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Fmoc-Cys(4-methoxytrityl)-OH requires storage at 2-8°C. As per its safety data, it is classified under WGK Germany 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area.
Is Fmoc-Cys(4-methoxytrityl)-OH a controlled substance?
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The provided data does not indicate that Fmoc-Cys(4-methoxytrityl)-OH is a controlled substance.
How is this product packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports fine chemicals globally, adhering to all relevant shipping regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a sample or quote for Fmoc-Cys(4-methoxytrityl)-OH?
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To request a sample or a quote for Fmoc-Cys(4-methoxytrityl)-OH, please contact our sales department through the website or by phone, referencing the product name and CAS number.
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