Fmoc-Cit-OH
Nα-Fmoc-L-citrulline (CAS: 133174-15-9), a derivative of the amino acid citrulline, is identified by the molecular formula C21H23N3O5 and a molecular weight of 397.42 g/mol. This compound is primarily utilised in peptide synthesis and chemical biology research. As a protected amino acid, it plays a crucial role in the controlled assembly of peptide chains, particularly in solid-phase peptide synthesis (SPPS) methodologies, contributing to the development of novel peptides and peptidomimetics.
- IUPAC
- Nα-Fmoc-L-citrulline
- Synonyms
- Nα-Fmoc-L-citrulline
Peptide Synthesis
Nα-Fmoc-L-citrulline is a key building block in solid-phase peptide synthesis (SPPS), allowing for the controlled incorporation of citrulline residues into peptide sequences. Its Fmoc protecting group facilitates orthogonal deprotection strategies in complex peptide assembly.
Chemical Biology Research
This unnatural amino acid derivative serves as a valuable tool in chemical biology for constructing peptides with modified structures or functionalities. It aids in studying protein-ligand interactions and developing novel bioactive peptides.
Analytical Standards
Nα-Fmoc-L-citrulline can be employed as an analytical standard in chromatography and other analytical techniques for the identification and quantification of citrulline-containing peptides or related compounds.
| Molecular weight | 397.42 |
|---|---|
| Empirical formula | C21H23N3O5 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Fmoc-L-citrulline used for?
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Nα-Fmoc-L-citrulline is primarily used as a building block in peptide synthesis and in chemical biology research for constructing modified peptides and studying biological processes.
What are the CAS number and formula for Nα-Fmoc-L-citrulline?
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The CAS number for Nα-Fmoc-L-citrulline is 133174-15-9, and its molecular formula is C21H23N3O5.
What grade and purity does Tech Serve Solutions supply for Nα-Fmoc-L-citrulline?
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Tech Serve Solutions supplies Nα-Fmoc-L-citrulline with a purity of ≥97.0% as determined by HPLC. This product is suitable for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for Nα-Fmoc-L-citrulline?
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When handling Nα-Fmoc-L-citrulline, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne concentrations are expected. The compound has a WGK Germany rating of 3, indicating a high hazard to water.
How is Nα-Fmoc-L-citrulline stored and shipped?
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Nα-Fmoc-L-citrulline should be stored at 2-8°C. Tech Serve Solutions can export this chemical globally, adhering to all necessary regulations for safe transport.
How can I request a quote or sample of Nα-Fmoc-L-citrulline?
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To request a quote or a sample of Nα-Fmoc-L-citrulline, please contact our sales department through the website or via email, providing your contact details and intended application.
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