Fmoc-Cys(Bzl)-OPfp

CAS 86060-95-9C31H22F5NO4SChemical Synthesis

Fmoc-Cys(Bzl)-OPfp, CAS 86060-95-9, is a derivative of the amino acid cysteine, featuring Fmoc protection on the amine and a benzyl protecting group on the thiol. Its empirical formula is C31H22F5NO4S and it has a molecular weight of 599.57 g/mol. This compound is primarily utilised in solid-phase peptide synthesis (SPPS) as a protected cysteine building block, enabling controlled incorporation into peptide chains.

IUPAC: Fmoc-S-benzyl-L-cysteine pentafluorophenyl ester
Synonyms: Fmoc-S-benzyl-L-cysteine pentafluorophenyl ester

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Fmoc-Cys(Bzl)-OPfp (C31H22F5NO4S) — chemical structure, CAS 86060-95-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisCysteine/CystinePeptide Chemistry

01 /Applications

Solid-Phase Peptide Synthesis

Fmoc-Cys(Bzl)-OPfp serves as a crucial building block in the Fmoc-based SPPS strategy. The benzyl group effectively protects the reactive thiol of cysteine during peptide assembly, preventing unwanted side reactions.

Chemical Biology Research

This derivative is employed in the synthesis of modified peptides for chemical biology studies. It allows for the site-specific introduction of cysteine residues with controlled thiol protection.

Custom Peptide Synthesis

Researchers and pharmaceutical companies utilise Fmoc-Cys(Bzl)-OPfp for the custom synthesis of peptides containing cysteine. The pentafluorophenyl ester offers good reactivity for coupling reactions.

02 /Properties

Molecular weight	599.57
Empirical formula	C31H22F5NO4S
Assay	≥98.0% (HPLC)
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

86060-95-9

MDL number

MFCD00237045

Beilstein registry

4649226

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Cys(Bzl)-OPfp used for?

Fmoc-Cys(Bzl)-OPfp is primarily used as a protected building block in solid-phase peptide synthesis (SPPS) and for general chemical synthesis involving cysteine.

What is the CAS number and molecular formula?

The CAS number for Fmoc-Cys(Bzl)-OPfp is 86060-95-9, and its empirical formula is C31H22F5NO4S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Cys(Bzl)-OPfp with an assay of ≥98.0% by HPLC. This product is supplied for research and laboratory use; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.

How should Fmoc-Cys(Bzl)-OPfp be handled safely?

Handle Fmoc-Cys(Bzl)-OPfp with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter, such as type N95 (US) or P1 (EN143), is recommended. This compound is classified under WGK 2 in Germany, indicating it is hazardous to aquatic life.

How is this chemical shipped and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Fmoc-Cys(Bzl)-OPfp. We adhere to all necessary regulations for the safe and compliant international shipment of laboratory reagents.

How can I request a sample or a quote?

To request a sample or obtain a quote for Fmoc-Cys(Bzl)-OPfp, please contact our sales department through the details provided on the Tech Serve Solutions website.