Fmoc-Asp-OAll
Fmoc-Asp-OAll (CAS 144120-53-6), with the molecular formula C22H21NO6 and a molecular weight of 395.41 g/mol, is a vital derivative of L-Aspartic acid. It features the Fmoc protecting group on the amine and the Allyl ester protecting group on the side chain carboxyl. This compound is instrumental in solid-phase peptide synthesis (SPPS) and solution-phase peptide chemistry for the controlled incorporation of aspartic acid residues.
- IUPAC
- Fmoc-L-aspartic acid 1-allyl ester
- Synonyms
- Fmoc-L-aspartic acid 1-allyl ester

Peptide Synthesis
Fmoc-Asp-OAll is widely used as a building block in solid-phase and solution-phase peptide synthesis. The orthogonal protecting groups allow for selective deprotection and coupling steps, enabling the construction of complex peptide sequences.
Chemical Biology Research
This aspartic acid derivative finds application in chemical biology for the synthesis of modified peptides and peptidomimetics. It aids in studying protein structure, function, and interactions.
Analytical Standards
Due to its defined structure and purity, Fmoc-Asp-OAll can serve as an analytical standard in chromatography and other analytical techniques for the identification and quantification of related compounds.
| Molecular weight | 395.41 |
|---|---|
| Empirical formula | C22H21NO6 |
| Assay | ≥97.0% (HPLC) |
| Optical activity | [α]20/D −24.5±2°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Asp-OAll used for?
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Fmoc-Asp-OAll is primarily used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis, allowing for the controlled incorporation of aspartic acid into peptide chains. It is also utilised in chemical biology research and as an analytical standard.
What is the CAS number and formula for Fmoc-Asp-OAll?
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The CAS number for Fmoc-Asp-OAll is 144120-53-6, and its empirical formula is C22H21NO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Asp-OAll with a purity of ≥97.0% as determined by HPLC. We do not represent this product as USP, BP, or EP grade.
How should Fmoc-Asp-OAll be handled and stored?
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Fmoc-Asp-OAll should be handled with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. It should be stored at 2-8°C to maintain its integrity.
How is Fmoc-Asp-OAll shipped or exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, including Fmoc-Asp-OAll, adhering to all relevant shipping and export regulations.
How can I request a sample or quote for Fmoc-Asp-OAll?
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To request a sample or a quote for Fmoc-Asp-OAll, please contact our sales team through the website or by telephone.
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