3-Chloro-4-hydroxyphenylacetic acid
3-Chloro-4-hydroxyphenylacetic acid (CAS 33697-81-3), with the chemical formula ClC6H3(OH)CH2CO2H and a molecular weight of 186.59 g/mol, is a key organic building block. This compound serves as a valuable intermediate in the synthesis of more complex molecules, particularly within the pharmaceutical and chemical research sectors. Its structure, featuring a chlorinated phenol ring and a carboxylic acid group, allows for diverse chemical transformations.

Organic Synthesis Intermediate
Utilised as a precursor in multi-step organic syntheses to construct novel chemical entities. Its functional groups enable a range of reactions crucial for creating complex molecular architectures.
Pharmaceutical Research
A building block employed in the development of new pharmaceutical compounds. It may be incorporated into synthetic routes targeting potential drug candidates.
Chemical Research and Development
Serves as a reagent in academic and industrial R&D laboratories for exploring new chemical reactions and materials. Its well-defined structure aids in predictable synthetic outcomes.
| Molecular weight | 186.59 |
|---|---|
| Linear formula | ClC6H3(OH)CH2CO2H |
| Assay | 99% |
| Melting point | 108-110 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-4-hydroxyphenylacetic acid used for?
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3-Chloro-4-hydroxyphenylacetic acid is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and chemical development.
What are the CAS number and chemical formula for 3-Chloro-4-hydroxyphenylacetic acid?
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The CAS number is 33697-81-3, and the chemical formula is ClC6H3(OH)CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloro-4-hydroxyphenylacetic acid with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
What are the safety precautions for handling 3-Chloro-4-hydroxyphenylacetic acid?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is 3-Chloro-4-hydroxyphenylacetic acid packed, shipped, and exported?
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We offer various packing options suitable for research and industrial quantities, adhering to international shipping regulations. TSS is a global supplier and exporter of fine chemicals.
How can I request a sample or a quote for 3-Chloro-4-hydroxyphenylacetic acid?
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Please contact our sales department via the website or direct email to request a sample or a quotation for 3-Chloro-4-hydroxyphenylacetic acid.
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