3-Chloro-4-fluorophenylzinc iodide solution
3-Chloro-4-fluorophenylzinc iodide solution (CAS 312624-19-4, Formula ClC6H3(F)ZnI, MW 321.83) is an organozinc halide reagent supplied by Tech Serve Solutions in a 0.5 M concentration in THF. This aryl compound is a valuable tool in organic synthesis, particularly for cross-coupling reactions. It is a flammable liquid that may form explosive peroxides and should be handled with appropriate safety precautions. It is exported globally by TSS.
Cross-Coupling Reactions
This organozinc halide is an effective nucleophile in various transition metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura or Negishi couplings. It enables the formation of carbon-carbon bonds by reacting with aryl or vinyl halides.
Organic Synthesis Intermediate
It serves as a versatile intermediate in the synthesis of complex organic molecules. The specific substitution pattern allows for the introduction of a 3-chloro-4-fluorophenyl moiety into diverse molecular scaffolds.
Preparation of Pharmaceuticals
This reagent can be utilized in the synthetic pathways for developing new pharmaceutical candidates where the 3-chloro-4-fluorophenyl group is a key structural element.
| Molecular weight | 321.83 |
|---|---|
| Linear formula | ClC6H3(F)ZnI |
| Boiling point | 65 °C |
| Density | 1.009 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-4-fluorophenylzinc iodide solution used for?
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3-Chloro-4-fluorophenylzinc iodide solution is primarily used as a reagent in organic synthesis, particularly for carbon-carbon bond formation via cross-coupling reactions and as an intermediate in the synthesis of complex organic molecules, including potential pharmaceuticals.
What is the CAS number and chemical formula for 3-Chloro-4-fluorophenylzinc iodide solution?
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The CAS number is 312624-19-4 and the chemical formula is ClC6H3(F)ZnI.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloro-4-fluorophenylzinc iodide solution at a concentration of 0.5 M in THF. We do not claim specific purity grades such as USP, BP, or EP unless explicitly stated in the product specifications. It is suitable for research and laboratory synthesis.
What are the main safety hazards associated with this product?
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This compound is a highly flammable liquid (H225) and may form explosive peroxides (Supplemental Hazard Statement). It can cause serious eye irritation (H319) and may cause respiratory irritation (H335). It is also suspected of causing cancer (H351). Handle with extreme caution in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment.
How is this product shipped and exported?
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3-Chloro-4-fluorophenylzinc iodide solution is classified under UN 2924, Hazard Class 8(3), Packing Group II, indicating it is a corrosive liquid, flammable, with a subsidiary risk. Tech Serve Solutions expertly handles all logistics for global export, adhering to international shipping regulations.
How can I request a sample or quote?
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To request a sample or a formal quote, please contact our sales department through the website or by calling us directly. Please specify the product name, CAS number, and desired quantity.
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