Boc-His(Bzl)-OH
Boc-His(Bzl)-OH (CAS: 20898-44-6), a derivative of L-histidine, presents as C18H23N3O4 with a molecular weight of 345.39 g/mol. This Nα-tert-butoxycarbonyl and N(im)-benzyl protected histidine is crucial in peptide synthesis. Its protected functional groups allow for controlled chain elongation, making it an indispensable building block in the preparation of complex peptides and peptidomimetics for research and development.
- IUPAC
- Nα-Boc-N(im)-benzyl-L-histidine
- Synonyms
- Nα-Boc-N(im)-benzyl-L-histidine
Peptide Synthesis
Serves as a protected amino acid building block for solid-phase or solution-phase peptide synthesis. The Boc and Benzyl protecting groups enable controlled coupling reactions in the construction of peptide chains.
Chemical Biology Research
Utilised in the synthesis of peptides with specific biological functions or modified structures for studying protein-protein interactions or enzyme mechanisms.
Pharmaceutical Intermediate
Can be employed in the multi-step synthesis of active pharmaceutical ingredients (APIs) where a histidine residue is part of the target molecule's structure.
Organic Synthesis
Acts as a chiral synthon in complex organic syntheses, leveraging the unique stereochemistry and functional groups of histidine.
| Molecular weight | 345.39 |
|---|---|
| Empirical formula | C18H23N3O4 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D +23±1°, c = 1% in methanol |
| Melting point | 181-184 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-His(Bzl)-OH used for?
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Boc-His(Bzl)-OH is primarily used as a protected amino acid building block in peptide synthesis and for applications in chemical biology research and pharmaceutical intermediate production.
What is the CAS number and formula for Boc-His(Bzl)-OH?
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The CAS number is 20898-44-6, and the empirical formula is C18H23N3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-His(Bzl)-OH with an assay of ≥98.0% (TLC). TSS does not represent this product as USP, BP, or EP grade.
How should Boc-His(Bzl)-OH be handled?
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Handle Boc-His(Bzl)-OH with appropriate personal protective equipment, including eyeshields, gloves, and a respirator filter (type N95 or P1). Ensure adequate ventilation.
Is Boc-His(Bzl)-OH a controlled substance?
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The provided data does not indicate that Boc-His(Bzl)-OH is a controlled substance.
How is Boc-His(Bzl)-OH packed and shipped?
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Boc-His(Bzl)-OH is carefully packed and exported by Tech Serve Solutions in compliance with international shipping regulations for chemical compounds.
How can I request a sample or quote for Boc-His(Bzl)-OH?
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To request a sample or a quote for Boc-His(Bzl)-OH, please contact the Tech Serve Solutions sales team via our website or listed contact information.
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