Boc-His-OH
Nα-(tert-Butoxycarbonyl)-L-histidine (CAS: 17791-52-5, C11H17N3O4) is a protected amino acid derivative widely utilized in chemical synthesis and peptide chemistry. With a molecular weight of 255.27 g/mol, this compound serves as a crucial building block for constructing complex peptides and related molecules. Its primary applications lie in research laboratories focused on organic synthesis, medicinal chemistry, and chemical biology, enabling precise modifications and the creation of novel biomolecules.
- IUPAC
- Nα-(tert-Butoxycarbonyl)-L-histidine,Nα-Boc-L-histidine
- Synonyms
- Nα-Boc-L-histidine
Peptide Synthesis
Serves as a protected amino acid for incorporation into peptide chains, allowing for controlled synthesis of biologically active peptides and peptidomimetics.
Medicinal Chemistry
Utilized in the development of new pharmaceutical agents by providing a modifiable histidine residue for drug discovery programs.
Chemical Biology Research
Employed in creating probes and modified biomolecules for studying biological processes and molecular interactions.
Organic Synthesis
Acts as a versatile intermediate in complex organic synthesis pathways, leveraging the protected functionality of histidine.
| Molecular weight | 255.27 |
|---|---|
| Empirical formula | C11H17N3O4 |
| Assay | 99% |
| Optical activity | [α]20/D +26°, c = 1 in methanol |
| Melting point | 195 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-His-OH used for?
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Nα-(tert-Butoxycarbonyl)-L-histidine (Boc-His-OH) is primarily used as a protected amino acid in peptide synthesis, medicinal chemistry research, chemical biology, and general organic synthesis.
What are the CAS number and formula for Boc-His-OH?
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The CAS number for Nα-(tert-Butoxycarbonyl)-L-histidine is 17791-52-5, and its empirical formula is C11H17N3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nα-(tert-Butoxycarbonyl)-L-histidine with an assay of 99%. This product is intended for research and technical use and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for Boc-His-OH?
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Handling Nα-(tert-Butoxycarbonyl)-L-histidine requires personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany 3, indicating a high hazard to water.
How is Boc-His-OH packed and shipped?
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Tech Serve Solutions exports and supplies Nα-(tert-Butoxycarbonyl)-L-histidine, adhering to all necessary regulations for safe packaging and international shipment.
How can I request a sample or quote for Boc-His-OH?
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To request a sample or a quote for Nα-(tert-Butoxycarbonyl)-L-histidine, please contact our sales department through the website or designated contact channels.
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