Cinchonidine
Cinchonidine (CAS 485-71-2), with the molecular formula C19H22N2O and a molecular weight of 294.39 g/mol, is a naturally occurring cinchona alkaloid. It is primarily utilised in asymmetric synthesis as a chiral ligand and resolving agent. This compound is recognised for its optical activity and is a valuable reagent in stereoselective chemical transformations, contributing to the development of enantiomerically pure compounds.
- IUPAC
- (−)-Cinchonidine
- Synonyms
- (-)-Cinchonidine
Chiral Resolution
Cinchonidine serves as a chiral resolving agent to separate enantiomers of racemic mixtures. Its ability to form diastereomeric salts with acidic compounds allows for their separation through crystallization.
Asymmetric Catalysis
As a chiral ligand, cinchonidine is employed in various asymmetric catalytic reactions. It can coordinate with metal centres to create chiral environments that promote enantioselective product formation.
Organic Synthesis
This alkaloid is a versatile building block and reagent in organic synthesis, particularly for reactions requiring chiral induction. It is used in the preparation of complex chiral molecules.
| Molecular weight | 294.39 |
|---|---|
| Empirical formula | C19H22N2O |
| Assay | 96% |
| Grade | purum |
| Optical activity | [α]23/D −109.2°, c = 1.5 in ethanol |
| Melting point | 204-206 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H361D
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-22-43-48/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CYP2D6(1565) |
|---|---|
| Target Organs | Heart, Immune system |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cinchonidine used for?
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Cinchonidine is primarily used in asymmetric synthesis as a chiral ligand and resolving agent, and in organic synthesis for creating chiral molecules.
What is the CAS number and molecular formula for Cinchonidine?
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The CAS number for Cinchonidine is 485-71-2, and its molecular formula is C19H22N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cinchonidine with a minimum assay of 96% (purum grade). We do not represent this product as USP, BP, or EP grade.
How should Cinchonidine be handled safely?
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Cinchonidine is classified with a Warning signal word and hazards including H302 (Harmful if swallowed), H317 (May cause an allergic skin reaction), H361d (Suspected of damaging fertility or the unborn child), and H373 (May cause damage to organs through prolonged or repeated exposure). Use appropriate personal protective equipment such as eyeshields, faceshields, gloves, and a type N95 or P1 respirator filter. Handle in well-ventilated areas.
Is Cinchonidine a controlled substance?
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The provided safety data does not indicate that Cinchonidine is a controlled substance. However, users should always verify regulatory status in their specific jurisdiction.
How is Cinchonidine packed and shipped?
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Cinchonidine is carefully packed and exported by Tech Serve Solutions to ensure product integrity and compliance with international shipping regulations for chemical compounds.
How can I request a sample or quote for Cinchonidine?
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To request a sample or a quote for Cinchonidine, please contact our sales team through the website or by phone.
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