Dimethyl 2-oxoglutarate
Dimethyl 2-oxoglutarate (CAS: 13192-04-6) is an organic compound with the molecular formula C7H10O5 and a molecular weight of 174.15 g/mol. This alpha-keto ester serves as a valuable building block in chemical synthesis, particularly within research focused on cancer metabolism and cell biology. Its structure, featuring both carbonyl and ester functionalities, makes it a versatile intermediate for creating more complex molecules.
- IUPAC
- Dimethyl α-ketoglutarate
- Synonyms
- Dimethyl α-ketoglutarate

Chemical Synthesis Intermediate
Dimethyl 2-oxoglutarate is employed as a key intermediate in organic synthesis, facilitating the construction of diverse molecular architectures. Its functional groups allow for various chemical transformations.
Cancer Research Reagent
This compound is utilised in studies investigating cancer metabolism and oncogenesis, particularly pathways involving glutamine. It can serve as a tool for exploring inhibitors and activators of metabolic pathways relevant to cancer.
Cell Biology Research
Researchers in cell biology may use Dimethyl 2-oxoglutarate to probe cellular metabolic processes. Its role in key metabolic pathways makes it relevant for understanding cell function and dysfunction.
| Molecular weight | 174.15 |
|---|---|
| Linear formula | CH3O2CCH2CH2COCO2CH3 |
| Assay | 96% |
| Boiling point | 90-95 °C/0.4 mmHg(lit.) |
| Density | 1.203 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.439(lit.) |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dimethyl 2-oxoglutarate used for?
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Dimethyl 2-oxoglutarate is primarily used as a building block in chemical synthesis and as a reagent in research related to cancer metabolism, cancer research, and cell biology. It is particularly relevant for studies involving glutamine metabolism and oncogenesis.
What is the CAS number and formula for Dimethyl 2-oxoglutarate?
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The CAS number for Dimethyl 2-oxoglutarate is 13192-04-6 and its linear formula is CH3O2CCH2CH2COCO2CH3.
What grade and purity does Tech Serve Solutions supply for Dimethyl 2-oxoglutarate?
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Tech Serve Solutions supplies Dimethyl 2-oxoglutarate with an assay of 96%. This is a technical/research grade product, and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for Dimethyl 2-oxoglutarate?
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When handling Dimethyl 2-oxoglutarate, it is essential to wear eyeshields and gloves. The compound has a flash point above 113 °C (235.4 °F) and is classified with WGK Germany 3, indicating a high degree of hazard in water.
How is Dimethyl 2-oxoglutarate packed and shipped?
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Dimethyl 2-oxoglutarate is available for packing and shipping worldwide. Please contact us for specific export details.
How can I request a sample or quote for Dimethyl 2-oxoglutarate?
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To request a sample or a quote for Dimethyl 2-oxoglutarate, please contact the Tech Serve Solutions sales team through our website or by phone.
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