Vinylmagnesium bromide solution
Vinylmagnesium bromide solution (CAS: 1826-67-1), with the linear formula CH2=CHMgBr and a molecular weight of 131.25 g/mol, is a highly reactive organometallic compound. It is supplied as a 1.0 M solution in Tetrahydrofuran (THF). As a Grignard reagent, it serves as a crucial building block in organic synthesis, facilitating the formation of new carbon-carbon bonds for creating complex molecules.
Organic Synthesis
Vinylmagnesium bromide is extensively used as a nucleophile in organic chemistry to introduce a vinyl group into various organic substrates. It is a key reagent in forming new carbon-carbon bonds, essential for building complex molecular architectures.
Pharmaceutical Intermediates
This Grignard reagent is employed in the multi-step synthesis of active pharmaceutical ingredients (APIs) and their precursors. Its ability to facilitate C-C bond formation is vital for constructing the carbon skeletons of drug molecules.
Fine Chemical Manufacturing
It acts as a versatile reagent in the production of various fine chemicals, including flavour and fragrance compounds, polymers, and speciality materials. Its reactivity allows for precise functionalisation of organic molecules.
Research and Development
Widely used in academic and industrial research laboratories for exploring novel synthetic routes and developing new chemical entities. Its predictable reactivity makes it a valuable tool for chemists.
| Molecular weight | 131.25 |
|---|---|
| Linear formula | CH2=CHMgBr |
| Density | 0.981 g/mL at 25 °C |
| Concentration | 1.0 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H260In contact with water releases flammable gases
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P223Do not allow contact with water
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P370In case of fire
- P422
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 2 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14/15-19-34-37 |
| Safety statements (S) | 16-26-36/37/39-43-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Vinylmagnesium bromide solution used for?
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Vinylmagnesium bromide solution is primarily used as a versatile nucleophile in organic synthesis to introduce a vinyl group via the formation of new carbon-carbon bonds. It is integral in the synthesis of pharmaceutical intermediates, fine chemicals, and in research and development laboratories.
What is the CAS number and formula for Vinylmagnesium bromide solution?
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The CAS number for Vinylmagnesium bromide solution is 1826-67-1, and its linear formula is CH2=CHMgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Vinylmagnesium bromide solution at a concentration of 1.0 M in THF. We do not represent this product as meeting pharmacopoeia standards (USP, BP, EP) unless explicitly stated.
How should Vinylmagnesium bromide solution be handled and stored?
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Vinylmagnesium bromide solution is highly flammable and reacts violently with water, releasing flammable gases. It causes severe skin burns and eye damage, and may cause respiratory irritation. Handle under an inert atmosphere, away from heat, sparks, and open flames. Wear appropriate personal protective equipment, including gloves, goggles, and a faceshield. Store in a cool, well-ventilated area, away from incompatible materials.
How is Vinylmagnesium bromide solution packed and shipped?
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Vinylmagnesium bromide solution is packed and shipped according to UN 3399, Hazard Class 4.3, Packing Group II regulations, ensuring safe transport and export.
How can I request a sample or quote for Vinylmagnesium bromide solution?
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To request a sample or quote for Vinylmagnesium bromide solution, please contact the Tech Serve Solutions sales team via our website or listed contact details, specifying the product and quantity required.
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