Cinchonine monohydrochloride hydrate
Cinchonine monohydrochloride hydrate (CAS: 206986-88-1) is a Cinchona alkaloid derivative with the empirical formula C19H22N2O · HCl · xH2O and a molecular weight of 330.85 g/mol on an anhydrous basis. This compound is primarily utilised in asymmetric synthesis and as a chiral catalyst or ligand. Its properties make it valuable for various chemical synthesis applications, offering a well-defined chiral structure for stereoselective transformations.
- IUPAC
- Cinchonan-9(S)-ol monohydrochloride

Chiral Catalysis
Cinchonine monohydrochloride hydrate serves as an effective chiral catalyst and ligand in asymmetric synthesis. It facilitates stereoselective reactions, enabling the production of enantiomerically enriched compounds crucial for pharmaceuticals and fine chemicals.
Asymmetric Synthesis
This compound is integral to asymmetric synthesis, where it helps control the stereochemical outcome of chemical reactions. Its application is vital for creating specific enantiomers of complex molecules.
Chemical Synthesis
As a versatile reagent, Cinchonine monohydrochloride hydrate finds application in diverse chemical synthesis pathways. It is employed in research and development for constructing novel chemical entities.
| Molecular weight | 330.85 (anhydrous basis) |
|---|---|
| Empirical formula | C19H22N2O · HCl · xH2O |
| Assay | 99% |
| Optical activity | [α]20/D +101°, c = 1 in chloroform |
| Melting point | 208-218 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cinchonine monohydrochloride hydrate used for?
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Cinchonine monohydrochloride hydrate is used in asymmetric synthesis, as a chiral catalyst and ligand, and in general chemical synthesis applications.
What is the CAS number and formula for Cinchonine monohydrochloride hydrate?
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The CAS number for Cinchonine monohydrochloride hydrate is 206986-88-1, and its empirical formula is C19H22N2O · HCl · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cinchonine monohydrochloride hydrate with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Cinchonine monohydrochloride hydrate?
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Cinchonine monohydrochloride hydrate is a Warning substance with hazards H302, H312, and H332 (Harmful if swallowed, in contact with skin, or if inhaled). Recommended PPE includes a dust mask type N95 (US), eyeshields, and gloves. Handle with appropriate ventilation and personal protective equipment.
How is Cinchonine monohydrochloride hydrate packed and shipped?
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Cinchonine monohydrochloride hydrate is carefully packed and exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.
How can I request a sample or quote for Cinchonine monohydrochloride hydrate?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
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