Boc-Gly-ONp
Boc-Gly-ONp (CAS: 3655-05-8), N-tert-butoxycarbonyl-glycine 4-nitrophenyl ester, is a derivative of the amino acid glycine with the chemical formula C13H16N2O6 and a molecular weight of 296.28 g/mol. This compound serves as a valuable reagent in organic synthesis, particularly in peptide chemistry. Its activated ester functionality allows for efficient coupling reactions, facilitating the formation of peptide bonds.
- IUPAC
- Boc-glycine 4-nitrophenyl ester
Peptide Synthesis
Boc-Gly-ONp is employed as an activated glycine derivative in solid-phase and solution-phase peptide synthesis. The 4-nitrophenyl ester group is a good leaving group, enabling facile coupling with the free amine of another amino acid or peptide chain.
Organic Synthesis Reagent
Beyond peptide synthesis, this compound can be utilized in general organic synthesis for introducing the Boc-protected glycine moiety into various molecules. Its reactivity makes it a useful building block in the construction of complex organic structures.
Chemical Biology Research
As a functionalized amino acid derivative, Boc-Gly-ONp finds applications in chemical biology for probing biological systems or creating modified peptides with specific functionalities.
| Molecular weight | 296.28 |
|---|---|
| Empirical formula | C13H16N2O6 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Gly-ONp used for?
+
Boc-Gly-ONp is primarily used in peptide synthesis as an activated glycine derivative for coupling reactions and in general organic synthesis for introducing a protected glycine unit.
What is the CAS number and chemical formula for Boc-Gly-ONp?
+
The CAS number is 3655-05-8 and the empirical formula is C13H16N2O6.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Boc-Gly-ONp with a purity of ≥98.0% (HPLC). TSS does not represent this product as USP, BP, EP or other pharmacopoeia grades unless explicitly stated.
How should Boc-Gly-ONp be handled and stored?
+
Handle Boc-Gly-ONp with appropriate personal protective equipment including eyeshields and gloves. Store at 2-8°C. The compound is classified under WGK Germany 3, indicating a high hazard to water.
Is Boc-Gly-ONp available for international export?
+
Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, including Boc-Gly-ONp.
How can I request a quote or sample of Boc-Gly-ONp?
+
Please contact our sales team via the website to request a quote or a sample of Boc-Gly-ONp.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis