Boc-Glu-OH
Boc-L-glutamic acid (CAS 2419-94-5) is a protected amino acid derivative with a molecular weight of 247.25 g/mol. This compound features the tert-butyloxycarbonyl (Boc) protecting group on the alpha-amino nitrogen of L-glutamic acid. It is primarily utilised in peptide synthesis and chemical biology research for controlled amino acid incorporation into peptide chains, ensuring regioselectivity during coupling reactions. Its specific structure makes it a valuable building block in complex organic synthesis.
- IUPAC
- Boc-L-glutamic acid
- Synonyms
- Boc-L-glutamic acidN-(tert-Butoxycarbonyl)-L-glutamic acid
Peptide Synthesis
Boc-L-glutamic acid serves as a key protected amino acid in solid-phase and solution-phase peptide synthesis. The Boc group facilitates controlled coupling by preventing unwanted reactions at the N-terminus, allowing for sequential addition of amino acids.
Chemical Biology
This compound is employed in chemical biology to synthesise modified peptides and proteins. Its unique structure allows for the introduction of glutamic acid residues into biomolecules, enabling studies of protein function and interactions.
Organic Synthesis
As a versatile building block, Boc-L-glutamic acid is used in the synthesis of complex organic molecules. Its protected amine and carboxylic acid functionalities can be selectively manipulated for the construction of novel chemical entities.
| Molecular weight | 247.25 |
|---|---|
| Linear formula | (CH3)3COCONHCH(COOH)CH2CH2COOH |
| Assay | ≥98.0% (T) |
| Optical activity | [α]20/D −14.5±2°, c = 1% in methanol |
| Storage temperature | 2-8°C |
| Melting point | ~110 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-L-glutamic acid used for?
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Boc-L-glutamic acid is primarily used in peptide synthesis and chemical biology for the controlled incorporation of glutamic acid into peptide chains and the synthesis of complex organic molecules.
What is the CAS number and molecular formula for Boc-L-glutamic acid?
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The CAS number is 2419-94-5. The linear formula is (CH3)3COCONHCH(COOH)CH2CH2COOH.
What grade and purity does Tech Serve Solutions supply for Boc-L-glutamic acid?
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Tech Serve Solutions supplies Boc-L-glutamic acid with an assay of ≥98.0% (T). We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should Boc-L-glutamic acid be handled and stored?
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Handle Boc-L-glutamic acid with appropriate personal protective equipment, including eyeshields and gloves. Store at 2-8°C to maintain its integrity. Refer to the safety data sheet for detailed handling information.
Is Boc-L-glutamic acid a controlled substance?
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The provided data does not indicate that Boc-L-glutamic acid is a controlled substance.
How can I request a quote or sample for Boc-L-glutamic acid?
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To request a quote or sample of Boc-L-glutamic acid, please contact our sales team through the website or by phone. We export globally and can arrange for delivery to your location.
What are the typical shipping and packaging conditions for Boc-L-glutamic acid?
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Boc-L-glutamic acid is typically shipped under controlled temperature conditions to maintain stability. Packaging is designed to ensure product integrity during domestic and international export.
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