Boc-Glu(OBzl)-OH
Boc-Glu(OBzl)-OH (CAS 13574-13-5) is a derivative of glutamic acid, featuring N-alpha-tert-butoxycarbonyl (Boc) protection and a benzyl ester at the side chain carboxyl. With a molecular weight of 337.37 g/mol, this compound is primarily utilised in peptide synthesis and chemical biology research. Its protected nature allows for controlled incorporation into peptide sequences, facilitating the construction of complex biomolecules and research probes.
- IUPAC
- Boc-L-glutamic acid 5-benzyl ester
Peptide Synthesis
Boc-Glu(OBzl)-OH serves as a protected building block in solid-phase and solution-phase peptide synthesis. The Boc group facilitates selective deprotection under mild acidic conditions, while the benzyl ester protects the side chain carboxyl group, which can be removed by hydrogenolysis.
Chemical Biology
This derivative is employed in the synthesis of modified peptides and peptidomimetics for studying biological processes. Its structure allows for the introduction of specific functionalities or the creation of probes for biochemical assays.
Organic Synthesis
As a functionalised amino acid derivative, Boc-Glu(OBzl)-OH can be used in various organic synthesis pathways. It provides a versatile starting material for the development of novel compounds with potential pharmaceutical or material science applications.
| Molecular weight | 337.37 |
|---|---|
| Linear formula | C6H5CH2OCOCH2CH2CH(COOH)NHCOOC(CH3)3 |
| Assay | ≥98.0% (T) |
| Optical activity | [α]20/D −5.5±0.5°, c = 1% in acetic acid |
| Storage temperature | 2-8°C |
| Melting point | 69-71 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Glu(OBzl)-OH used for?
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Boc-Glu(OBzl)-OH is principally used as a protected amino acid derivative in peptide synthesis and chemical biology research. It acts as a building block for creating peptide chains and modified biomolecules.
What are the CAS number and formula for Boc-Glu(OBzl)-OH?
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The CAS number for Boc-Glu(OBzl)-OH is 13574-13-5. Its linear formula is C <sub>6</sub>H<sub>5</sub>CH<sub>2</sub>OCOCH<sub>2</sub>CH<sub>2</sub>CH(COOH)NHCOOC(CH<sub>3</sub>)<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Glu(OBzl)-OH with an assay of ≥98.0% (T). We do not represent this product as USP, BP, EP, or any pharmacopoeial grade.
How should Boc-Glu(OBzl)-OH be handled and stored?
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This compound should be handled with appropriate personal protective equipment, including eyeshields and gloves. It is classified under WGK 3 in Germany and should be stored at 2-8°C to maintain its integrity.
Is Boc-Glu(OBzl)-OH a controlled substance?
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Based on the provided data, Boc-Glu(OBzl)-OH is not listed as a controlled substance.
How can I request a sample or quote for Boc-Glu(OBzl)-OH?
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To request a sample or a quote for Boc-Glu(OBzl)-OH, please contact our sales team through the website or by phone. We are a global supplier and exporter.
How is Boc-Glu(OBzl)-OH packaged and shipped?
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Boc-Glu(OBzl)-OH is carefully packaged to ensure stability during transport and is available for global export. Specific packaging details can be discussed upon order.
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