Boc-GABA-OH
Boc-GABA-OH (CAS: 57294-38-9; Formula: C9H17NO4; MW: 203.24) is a protected form of gamma-aminobutyric acid (GABA). This derivative is valuable in organic synthesis and peptide chemistry. Its Boc-protecting group allows for selective reactions, making it a key intermediate in the synthesis of complex molecules, including peptides and peptidomimetics, where controlled amino acid incorporation is crucial.
- IUPAC
- γ-(Boc-amino)butyric acid,4-(tert-Butoxycarbonylamino)butyric acid,Boc-GABA
- Synonyms
- 4-(tert-Butoxycarbonylamino)butyric acidγ-(Boc-amino)butyric acidBoc-GABA
Peptide Synthesis
Boc-GABA-OH serves as a building block in solid-phase and solution-phase peptide synthesis. The tert-Butoxycarbonyl (Boc) protecting group ensures controlled coupling reactions, enabling the sequential addition of amino acids to construct peptide chains.
Chemical Synthesis Intermediate
This compound is utilized as an intermediate in the synthesis of various organic molecules. Its functional groups allow for diverse chemical transformations, contributing to the creation of novel chemical entities in research and development settings.
Drug Discovery Research
As an unnatural amino acid derivative, Boc-GABA-OH is employed in the design and synthesis of peptidomimetics and modified peptides for drug discovery programs, aiming to improve pharmacokinetic properties or receptor binding.
Chemical Biology Studies
It finds application in chemical biology for constructing labelled peptides or probes. This aids in studying biological processes, protein-ligand interactions, and enzyme activity at a molecular level.
| Molecular weight | 203.24 |
|---|---|
| Empirical formula | C9H17NO4 |
| Assay | 97% |
| Boiling point | 78-82 °C/0.2 mmHg(lit.) |
| Melting point | 55-57 °C(lit.) |
| Flash point | 113 °C / 235.4 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-GABA-OH used for?
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Boc-GABA-OH is primarily used as a protected amino acid building block in peptide synthesis, an intermediate in organic and chemical synthesis, and in drug discovery research and chemical biology studies.
What is the CAS number and formula for Boc-GABA-OH?
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The CAS number for Boc-GABA-OH is 57294-38-9, and its empirical formula (Hill notation) is C9H17NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-GABA-OH with an assay of 97%. This product is typically supplied as a research or technical grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling considerations for Boc-GABA-OH?
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Boc-GABA-OH has a flash point of 113 °C (235.4 °F) and a WGK rating of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area, avoiding contact with skin, eyes, and clothing. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
How is Boc-GABA-OH packed, shipped, and exported?
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Boc-GABA-OH is carefully packed to ensure product integrity during transit. As a global supplier, Tech Serve Solutions handles all necessary documentation for reliable international export to meet regulatory requirements.
How can I request a sample or quote for Boc-GABA-OH?
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To request a sample or a quote for Boc-GABA-OH, please contact our sales team through the website or by phone. Provide your specific requirements, and we will respond promptly.
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