8-(3-Chlorostyryl)caffeine
8-(3-Chlorostyryl)caffeine (CAS: 147700-11-6) is a crystalline organic compound with the formula C16H15ClN4O2 and a molecular weight of 330.77 g/mol. This chemical serves as a potent antagonist for adenosine receptors, specifically targeting the A1 and A2A subtypes. It is utilised in biochemical research, particularly in studies related to cell signalling and neuroscience. Its properties make it a valuable tool for investigating purinergic signalling pathways.
- IUPAC
- 1,3,7-Trimethyl-8-(3-chlorostyryl)xanthine,CSC
- Synonyms
- 1,3,7-Trimethyl-8-(3-chlorostyryl)xanthine, CSC

Adenosine Receptor Antagonist
8-(3-Chlorostyryl)caffeine functions as a selective antagonist for adenosine receptors, primarily A1 and A2A subtypes. This makes it valuable for research into the roles of these receptors in various physiological processes.
Neuroscience Research
The compound is employed in neuroscience to study neurotransmission and neuronal signalling pathways involving adenosine receptors. Its ability to block these receptors aids in understanding their impact on the central nervous system.
Cell Signalling Studies
As a tool in cell biology, it helps researchers elucidate the mechanisms of cell signalling mediated by purinergic receptors. It allows for the investigation of downstream effects of adenosine receptor activation or blockade.
Biochemical Research Reagent
This molecule is a useful reagent in biochemical assays designed to probe receptor function and ligand binding. Its defined antagonist activity provides a controlled method for studying receptor-mediated responses.
| Molecular weight | 330.77 |
|---|---|
| Empirical formula | C16H15ClN4O2 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >5 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADORA2A(135)mouse ... Maob(109731)rat ... Adora1(29290), Adora2a(25369) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 8-(3-Chlorostyryl)caffeine used for?
+
8-(3-Chlorostyryl)caffeine is used primarily as a research chemical, particularly as an antagonist for adenosine receptors (A1 and A2A subtypes) in studies related to neuroscience, cell signalling, and biochemical research.
What are the CAS number and molecular formula for 8-(3-Chlorostyryl)caffeine?
+
The CAS number for 8-(3-Chlorostyryl)caffeine is 147700-11-6, and its molecular formula is C16H15ClN4O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 8-(3-Chlorostyryl)caffeine with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, or EP grade.
How should 8-(3-Chlorostyryl)caffeine be handled and stored?
+
Handle 8-(3-Chlorostyryl)caffeine with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store the compound at -20°C. The German WGK classification is 3.
Is 8-(3-Chlorostyryl)caffeine a controlled substance?
+
The provided data does not indicate that 8-(3-Chlorostyryl)caffeine is a controlled substance.
How is 8-(3-Chlorostyryl)caffeine shipped and exported?
+
Tech Serve Solutions, a specialist global supplier and exporter since 1998, handles the packing, shipping, and export of 8-(3-Chlorostyryl)caffeine in compliance with all relevant regulations for chemical products.
How can I request a sample or quote for 8-(3-Chlorostyryl)caffeine?
+
To request a sample or quote for 8-(3-Chlorostyryl)caffeine, please contact the Tech Serve Solutions sales team through our website or by phone.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents

(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis