8(R)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid
8(R)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid (CAS 105500-09-2) is a polyunsaturated fatty acid with the molecular formula C20H32O3. As a hydroxy fatty acid and an omega-6 derivative, it serves as a valuable biochemical reagent. It is typically supplied as a research-grade chemical, crucial for studies in lipid metabolism and related biological pathways.
- IUPAC
- 8(R)-HETE
- Synonyms
- 14Z)-eicosatetraenoic acid8(R)-HETE

Biochemical Research
Utilised as a standard or substrate in biochemical and lipid research. Its specific stereochemistry and fatty acid chain make it relevant for investigating enzymatic pathways and signal transduction.
Metabolic Pathway Studies
Essential for studying the metabolism of fatty acids, particularly the omega-6 family. It can be used to identify and quantify specific metabolites in biological samples.
Analytical Standard
Serves as an analytical standard for the identification and quantification of hydroxy fatty acids in complex biological matrices using techniques like LC-MS or GC-MS.
| Molecular weight | 320.47 |
|---|---|
| Empirical formula | C20H32O3 |
| Assay | ~98% |
| Concentration | ~100 μg/mL in ethanol |
| Storage temperature | −20°C |

Hazard statements
- H225Highly flammable liquid and vapour
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 14 °C / 57.2 °F |
| Transport (UN / ADR) | UN 1170C 3 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F |
| Risk statements (R) | 11 |
| Safety statements (S) | 7-16 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 8(R)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid used for?
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This compound is primarily used in biochemical research, metabolic pathway studies, and as an analytical standard for identifying and quantifying hydroxy fatty acids in biological samples.
What is the CAS number and molecular formula for 8(R)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid?
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The CAS number is 105500-09-2 and the molecular formula is C20H32O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of approximately 98%. It is considered a research-grade chemical and is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling precautions for this chemical?
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This compound is highly flammable (H225) and requires careful handling. It necessitates the use of safety equipment including eyeshields, faceshields, and appropriate respirator filters (type ABEK). Store at -20°C and keep away from ignition sources.
How is 8(R)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid shipped?
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This product is shipped in dry ice to maintain its stability during transport.
How can I request a sample or quote?
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Please contact our sales team via the website or direct email to request a sample or a formal quotation for 8(R)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid.
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