7-Nitroindazole
7-Nitroindazole (CAS: 2942-42-9), with the molecular formula C7H5N3O2 and a molecular weight of 163.13 g/mol, is a key organic compound. It is recognised for its role as an inhibitor of nitric oxide synthase (NOS) enzymes. This property makes it a valuable tool in biochemical research, particularly for studying cellular signalling pathways and the metabolism of nitric oxide in various biological systems.
- IUPAC
- 7-NI
Nitric Oxide Synthase Inhibition
7-Nitroindazole serves as a potent inhibitor for nitric oxide synthase (NOS) enzymes, including NOS1, NOS2, and NOS3. This characteristic is critical for research into the physiological and pathological roles of nitric oxide in biological systems.
Cellular Signalling Research
As a bioactive small molecule, 7-Nitroindazole is employed in studies investigating cell signalling pathways. Its ability to modulate NOS activity provides insights into cellular communication and responses in various biological contexts.
Biochemical Reagent
This compound functions as a valuable biochemical reagent in laboratories. Its defined purity allows for reliable use in experiments aimed at understanding enzyme kinetics and molecular interactions.
| Molecular weight | 163.13 |
|---|---|
| Empirical formula | C7H5N3O2 |
| Assay | ≥98% |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
- H319Causes serious eye irritation
- H351Suspected of causing cancer
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P281Use personal protective equipment as required
- P301IF SWALLOWED
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 60-40 |
| Safety statements (S) | 53-22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)rat ... Nos1(24598) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7-Nitroindazole used for?
+
7-Nitroindazole is primarily used as an inhibitor of nitric oxide synthase (NOS) enzymes in biochemical and cell biology research, aiding studies on cell signalling and nitric oxide metabolism.
What are the CAS number and chemical formula for 7-Nitroindazole?
+
The CAS number for 7-Nitroindazole is 2942-42-9, and its chemical formula is C7H5N3O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 7-Nitroindazole with an assay of ≥98%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 7-Nitroindazole be handled?
+
7-Nitroindazole is classified as dangerous. It is toxic if swallowed (H301), causes serious eye irritation (H319), and is suspected of causing cancer (H351) and may damage fertility or the unborn child (H360). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., P3 filter), must be used. Handle with extreme caution in a well-ventilated area.
Is 7-Nitroindazole a controlled substance?
+
The provided data does not indicate that 7-Nitroindazole is a controlled substance.
How is 7-Nitroindazole packed, shipped, and exported?
+
7-Nitroindazole is shipped according to international regulations for hazardous materials, marked as UN 2811 (Toxic solid, organic, n.o.s.) Class 6.1, Packing Group III.
How can I request a quote or sample for 7-Nitroindazole?
+
To request a quote or a sample of 7-Nitroindazole, please contact our sales department through the TSS website or via direct inquiry.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents
(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis