8(S)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid
8(S)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid (CAS 98462-03-4), a C20H32O3 lipid with a molecular weight of 320.47 g/mol, is a biologically active oxylipin. It is a key intermediate in the arachidonic acid cascade, involved in various cellular processes. This compound is supplied by Tech Serve Solutions for research applications in cell biology and signalling.
- IUPAC
- 8(S)-HETE
- Synonyms
- 8(S)-HETE(5Z,9E,11Z,14Z)-8-Hydroxyicosatetraenoic acid8(S)-Hydroxyarachidonic acid

Research in Cell Signalling
8(S)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid serves as a valuable reagent for investigating signal transduction pathways within cells. Its role in the arachidonic acid cascade makes it pertinent for studies on inflammation and immune responses.
Biochemical Research
This compound is utilised in biochemical studies to understand lipid metabolism and the enzymatic pathways that generate oxylipins. Researchers can employ it to elucidate the functions of hydroxy fatty acids in cellular homeostasis.
Neuroscience Investigations
As a component of the arachidonic acid cascade, 8(S)-HETE may play a role in neuronal function. Its application can support research into lipid mediators in the central nervous system.
| Molecular weight | 320.47 |
|---|---|
| Empirical formula | C20H32O3 |
| Assay | ~98% (HPLC) |
| Concentration | ~100 μg/mL in ethanol |
| Storage temperature | −20°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 1170 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 8(S)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid used for?
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8(S)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid is primarily used in biochemical research, particularly for studies involving the arachidonic acid cascade, cell signalling, and lipid metabolism. It is suitable for investigating cellular processes and inflammatory responses.
What are the CAS number and formula for this compound?
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The CAS number is 98462-03-4, and the empirical formula is C20H32O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 8(S)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid with an assay of approximately 98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or any pharmacopoeial grade.
What are the safety and handling recommendations?
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This compound is classified with GHS07 and carries a Warning signal word. It has hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used. Handle in a well-ventilated area and avoid inhalation of dust or vapours.
How is this chemical shipped?
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8(S)-Hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoic acid is shipped on dry ice.
How can I request a quote or sample?
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To request a quote or sample, please contact Tech Serve Solutions directly through our website or by calling our sales department. Our team will be pleased to assist you.
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