2-Chloro-4-fluoroaniline
2-Chloro-4-fluoroaniline (CAS: 2106-02-7), with the molecular formula ClC6H3(F)NH2 and a molecular weight of 145.56 g/mol, is a fluorinated aromatic amine. This chemical serves as a valuable building block in organic synthesis. It is commonly employed in the development of pharmaceuticals, agrochemicals, and advanced materials where specific halogenation patterns are required for desired molecular properties.

Pharmaceutical Intermediates
Used in the synthesis of active pharmaceutical ingredients (APIs). Its unique structure allows for the introduction of both chlorine and fluorine atoms into drug molecules, influencing their pharmacokinetic and pharmacodynamic profiles.
Agrochemical Development
Serves as a precursor for various pesticides and herbicides. The presence of halogens can enhance the efficacy and selectivity of agrochemical compounds.
Material Science
Incorporated into the synthesis of specialty polymers and advanced materials. The fluorinated aromatic moiety can impart desirable properties such as thermal stability and chemical resistance.
Research and Development
A versatile reagent for organic chemists exploring new synthetic routes and novel compound discovery in academic and industrial research settings.
| Molecular weight | 145.56 |
|---|---|
| Linear formula | ClC6H3(F)NH2 |
| Assay | 99% |
| Boiling point | 192 °C(lit.) |
| Density | 1.219 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.554(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-fluoroaniline primarily used for?
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2-Chloro-4-fluoroaniline is primarily used as a building block in organic synthesis for the development of pharmaceuticals, agrochemicals, and advanced materials.
What are the CAS number and molecular formula for 2-Chloro-4-fluoroaniline?
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The CAS number is 2106-02-7 and the molecular formula is ClC6H3(F)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4-fluoroaniline with a purity of 99% assay. We do not represent this product as USP, BP, or EP grade.
How should 2-Chloro-4-fluoroaniline be handled safely?
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2-Chloro-4-fluoroaniline is harmful if swallowed, in contact with skin, and if inhaled. It also causes skin irritation, serious eye irritation, and may cause respiratory irritation. Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and handle in a well-ventilated area.
Is 2-Chloro-4-fluoroaniline a controlled substance?
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Based on the provided data, there is no indication that 2-Chloro-4-fluoroaniline is a controlled substance.
How is 2-Chloro-4-fluoroaniline packed and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packing and export details will be provided upon inquiry, adhering to international shipping regulations.
How can I request a quote or sample for 2-Chloro-4-fluoroaniline?
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Please contact our sales team via the website or direct inquiry channels to request a quote or sample of 2-Chloro-4-fluoroaniline.
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