2-Chloro-4-fluorobenzoic acid
2-Chloro-4-fluorobenzoic acid (CAS: 2252-51-9), with the molecular formula ClC6H3(F)CO2H and a molecular weight of 174.56 g/mol, is a valuable organic compound. This versatile building block is characterised by its carboxylic acid functionality alongside chlorine and fluorine substituents on the benzene ring. It finds application in chemical synthesis, particularly as an intermediate in the preparation of more complex organic molecules, including heterocyclic compounds.
Organic Synthesis Intermediate
2-Chloro-4-fluorobenzoic acid serves as a key intermediate in the synthesis of various organic compounds. Its reactive sites allow for diverse chemical transformations, making it useful in constructing complex molecular architectures.
Preparation of Heterocyclic Compounds
This compound has been utilised in the preparation of specific heterocyclic systems, such as benzothiazoles. Its structure is well-suited for incorporation into fused ring systems through established synthetic routes.
Fluorinated Building Block
As a fluorinated aromatic compound, it is employed in research and development for creating novel fluorinated molecules. The fluorine atom can impart unique properties to the final product, influencing factors like lipophilicity and metabolic stability.
| Molecular weight | 174.56 |
|---|---|
| Linear formula | ClC6H3(F)CO2H |
| Assay | 99% |
| Solubility | 95% ethanol: soluble50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow |
| Application | 2-Chloro-4-fluorobenzoic acid was used in the preparation of 2-(2-chloro-4-fluorophenyl)-benzothiazole1. |
| Melting point | 181-183 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-fluorobenzoic acid used for?
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2-Chloro-4-fluorobenzoic acid is used as an intermediate in organic synthesis, particularly for preparing heterocyclic compounds like 2-(2-chloro-4-fluorophenyl)-benzothiazole. It functions as a valuable building block in chemical research and development.
What are the CAS number and formula for 2-Chloro-4-fluorobenzoic acid?
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The CAS number for 2-Chloro-4-fluorobenzoic acid is 2252-51-9, and its molecular formula is ClC6H3(F)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4-fluorobenzoic acid with an assay of 99%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and chemical synthesis applications.
How should 2-Chloro-4-fluorobenzoic acid be handled safely?
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2-Chloro-4-fluorobenzoic acid is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves, must be worn. Ensure adequate ventilation and avoid breathing dust.
Is 2-Chloro-4-fluorobenzoic acid exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Chloro-4-fluorobenzoic acid, to customers worldwide.
How can I request a quote or sample for 2-Chloro-4-fluorobenzoic acid?
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To request a quote or sample for 2-Chloro-4-fluorobenzoic acid, please contact our sales department via the website or phone, providing your specific requirements.
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