2-Chloro-4-fluorobenzonitrile
2-Chloro-4-fluorobenzonitrile (CAS: 60702-69-4), with the molecular formula ClC6H3(F)CN and a molecular weight of 155.56 g/mol, is a valuable organic building block. It is frequently employed in the synthesis of complex organic molecules, particularly within the pharmaceutical and agrochemical sectors. Its structure, featuring both a nitrile group and halogen substituents on an aromatic ring, makes it a versatile intermediate for various chemical transformations.
Pharmaceutical Intermediate
2-Chloro-4-fluorobenzonitrile serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its reactive sites allow for the introduction of diverse functionalities required in drug discovery and development.
Agrochemical Synthesis
This compound is utilized in the development of novel agrochemicals. The presence of fluorine and chlorine atoms can impart desirable properties such as enhanced efficacy and metabolic stability to the final products.
Material Science Research
The unique electronic properties conferred by the halogens and nitrile group make 2-Chloro-4-fluorobenzonitrile a potential precursor for advanced materials. It can be incorporated into polymers or used in the synthesis of functional organic materials.
Organic Synthesis Building Block
As a versatile building block, it enables chemists to construct intricate molecular architectures. It is used in various cross-coupling reactions and nucleophilic substitution processes.
| Molecular weight | 155.56 |
|---|---|
| Linear formula | ClC6H3(F)CN |
| Assay | 99% |
| Melting point | 64-66 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-fluorobenzonitrile used for?
+
2-Chloro-4-fluorobenzonitrile is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and potentially in material science. It serves as a versatile building block in organic chemistry.
What is the CAS number and molecular formula for 2-Chloro-4-fluorobenzonitrile?
+
The CAS number is 60702-69-4 and the molecular formula is ClC6H3(F)CN.
What grade and purity does Tech Serve Solutions supply for 2-Chloro-4-fluorobenzonitrile?
+
Tech Serve Solutions supplies 2-Chloro-4-fluorobenzonitrile with an assay of 99%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2-Chloro-4-fluorobenzonitrile be handled safely?
+
Handle 2-Chloro-4-fluorobenzonitrile with appropriate personal protective equipment, including a dust mask (type N95 recommended), eyeshields, and gloves. Ensure adequate ventilation to avoid inhalation of dust. It is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, as well as respiratory irritation (H302, H312, H332, H315, H319, H335).
How is 2-Chloro-4-fluorobenzonitrile packed, shipped, and exported?
+
2-Chloro-4-fluorobenzonitrile is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions. Specific packaging details will be provided upon order.
How can I request a quote or sample of 2-Chloro-4-fluorobenzonitrile?
+
To request a quote or sample of 2-Chloro-4-fluorobenzonitrile, please contact our sales department through the website or by phone. Our team will be pleased to assist you.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis