2-Chloro-4-fluorobenzoyl chloride
2-Chloro-4-fluorobenzoyl chloride (CAS: 21900-54-9), with the molecular formula C7H3Cl2FO and a molecular weight of 193.00 g/mol, is a reactive acid halide. It serves as a crucial intermediate and building block in organic synthesis, particularly for introducing the 2-chloro-4-fluorobenzoyl moiety into complex molecules. Its applications are primarily within the chemical and pharmaceutical research sectors for the development of novel compounds.
Pharmaceutical Intermediate
2-Chloro-4-fluorobenzoyl chloride is utilised in the synthesis of various active pharmaceutical ingredients (APIs). It enables the incorporation of its specific chemical structure into drug candidates during research and development phases.
Agrochemical Synthesis
This compound acts as a key building block in the development of new agrochemicals. It facilitates the creation of molecules with potential herbicidal, fungicidal, or insecticidal properties.
Organic Synthesis Reagent
As a versatile acylating agent, 2-Chloro-4-fluorobenzoyl chloride is employed in general organic synthesis for creating complex organic molecules. Its reactivity allows for efficient functionalisation in multi-step synthetic pathways.
Materials Science
The compound may find applications in the synthesis of specialised polymers or functional materials where its specific structural features are desired to impart unique properties.
| Molecular weight | 193.00 |
|---|---|
| Empirical formula | C7H3Cl2FO |
| Assay | 97% |
| Density | 1.447 g/mL at 25 °C |
| Refractive index | n20/D 1.551 |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-fluorobenzoyl chloride used for?
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2-Chloro-4-fluorobenzoyl chloride is used as an intermediate and building block in organic synthesis, primarily in the pharmaceutical and agrochemical industries, as well as in materials science research.
What are the CAS number and formula for 2-Chloro-4-fluorobenzoyl chloride?
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The CAS number is 21900-54-9 and the empirical formula is C7H3Cl2FO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4-fluorobenzoyl chloride with an assay of 97%. This is a technical grade suitable for research and synthesis, and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should 2-Chloro-4-fluorobenzoyl chloride be handled?
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2-Chloro-4-fluorobenzoyl chloride is classified as Danger with hazards including harmful if swallowed (H302) and causes severe skin burns and eye damage (H314). It requires careful handling with appropriate personal protective equipment, including gloves, goggles, face shields, and suitable respiratory protection. Handle in a well-ventilated area.
How is 2-Chloro-4-fluorobenzoyl chloride packed and shipped?
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2-Chloro-4-fluorobenzoyl chloride is packed in accordance with international shipping regulations, including UN 3265 classification for corrosive liquid, acidic, organic, n.o.s. (2-Chloro-4-fluorobenzoyl chloride), Packing Group II. TSS exports this chemical globally.
How can I request a sample or quote for 2-Chloro-4-fluorobenzoyl chloride?
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To request a sample or a quote for 2-Chloro-4-fluorobenzoyl chloride, please contact the Tech Serve Solutions sales team through our website or by phone. Please specify the quantity required.
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