Chlorodiethylisopropylsilane
Chlorodiethylisopropylsilane (CAS: 107149-56-4) is an organosilicon compound with the linear formula (CH3)2CHSi(C2H5)2Cl and a molecular weight of 164.75 g/mol. This reagent is primarily utilised in chemical synthesis, particularly as a protecting and derivatizing agent in organic chemistry. Its silicon-based structure and reactive chloride atom make it valuable for introducing specific functional groups or protecting sensitive moieties during complex synthetic procedures.

Protecting Group Chemistry
Chlorodiethylisopropylsilane serves as an effective reagent for the protection of various functional groups, such as alcohols, in multi-step organic syntheses. Its unique steric bulk can influence reactivity and stability.
Derivatization Agent
The compound can be employed to derivatize molecules, altering their properties for analytical purposes or facilitating further chemical transformations. It is particularly useful in the synthesis of silicon-containing compounds.
Specialty Chemical Synthesis
As a silicon-based synthetic reagent, Chlorodiethylisopropylsilane finds application in the construction of complex organic molecules where the precise introduction of organosilicon fragments is required.
| Molecular weight | 164.75 |
|---|---|
| Linear formula | (CH3)2CHSi(C2H5)2Cl |
| Assay | 98% |
| Boiling point | 73 °C/32 mmHg(lit.) |
| Density | 0.892 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.438(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H261In contact with water releases flammable gas
- H314Causes severe skin burns and eye damage
Precautionary statements
- P231Handle under inert gas
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
- P422
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 37 °C / 98.6 °F |
| Transport (UN / ADR) | UN 3094 8/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-14-34 |
| Safety statements (S) | 7/8-16-26-36/37/39-43-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorodiethylisopropylsilane used for?
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Chlorodiethylisopropylsilane is used in chemical synthesis, primarily as a protecting and derivatizing reagent, especially in organic chemistry and the synthesis of silicon-containing compounds.
What is the CAS number and formula for Chlorodiethylisopropylsilane?
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The CAS number is 107149-56-4 and the linear formula is (CH3)2CHSi(C2H5)2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chlorodiethylisopropylsilane with a minimum assay of 98%. This product is intended for laboratory and industrial use and is not represented as USP, BP, or EP grade.
How should Chlorodiethylisopropylsilane be handled safely?
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Chlorodiethylisopropylsilane is a dangerous substance that reacts violently with water, is flammable, and causes severe skin burns and eye damage. Handle with extreme caution, wearing full protective equipment including faceshields, gloves, and appropriate respirators. Ensure work is conducted in a well-ventilated area away from moisture and ignition sources.
How is Chlorodiethylisopropylsilane packed, shipped, and exported?
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As per UN 3094 regulations, Chlorodiethylisopropylsilane is shipped as a Class 8, Packing Group II hazardous material, requiring specialised packaging and handling procedures for safe transport and export.
How can I request a sample or quote for Chlorodiethylisopropylsilane?
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To request a sample or a quotation for Chlorodiethylisopropylsilane, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.
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