2,4-Dibromothiazole
2,4-Dibromothiazole (CAS: 4175-77-3) is a halogenated heterocyclic compound with the molecular formula C3HBr2NS and a molecular weight of 242.92 g/mol. As a vital chemical building block, it plays a significant role in organic synthesis, particularly in the development of complex molecules. Its utility is demonstrated in the synthesis of biologically active compounds and advanced materials, offering chemists a versatile reagent for further functionalisation and structural elaboration.
- Synonyms
- C3HBr2NS

Organic Synthesis Reagent
2,4-Dibromothiazole serves as a key building block in multi-step organic synthesis. Its reactive bromine atoms allow for diverse coupling reactions and functional group transformations.
Pharmaceutical Intermediate
This compound is utilised in the preparation of novel pharmaceutical agents. It can be incorporated into molecular scaffolds for the development of new drug candidates.
Material Science
The thiazole core, functionalised with bromine, makes it a potential precursor for functional materials, including organic electronics and polymers.
| Molecular weight | 242.92 |
|---|---|
| Empirical formula | C3HBr2NS |
| Assay | 97% |
| Application | Building block in a synthesis of Melithiazole C employing a highly (E)-selective cross-metathesis between the derived 4-vinylthiazole and a dienote side-chain.1 |
| Melting point | 80-84 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Dibromothiazole used for?
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2,4-Dibromothiazole is primarily used as a building block in organic synthesis for the preparation of pharmaceuticals, agrochemicals, and advanced materials. It has been notably employed in the synthesis of Melithiazole C.
What is the CAS number and formula for 2,4-Dibromothiazole?
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The CAS number is 4175-77-3 and the empirical formula is C3HBr2NS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Dibromothiazole with a minimum purity of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 2,4-Dibromothiazole be handled safely?
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2,4-Dibromothiazole is classified as a Danger. It is harmful if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation (H302-H315-H318-H335). Use a dust mask type N95 (US), eyeshields, faceshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
Does TSS export 2,4-Dibromothiazole?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,4-Dibromothiazole.
How can I request a quote or sample for 2,4-Dibromothiazole?
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To request a quote or sample of 2,4-Dibromothiazole, please contact our sales team via the website or by phone.
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