2,4-Dichloro-1-naphthol
2,4-Dichloro-1-naphthol (CAS 2050-76-2) is a chlorinated naphthol derivative with the molecular formula Cl2C10H5OH and a molecular weight of 213.06 g/mol. It serves as a valuable intermediate and reagent in organic synthesis. This compound has found application in the spectrophotometric determination of arginine and in assays for guanidinoacetate and guanidinosuccinate, which can serve as indicators of kidney dysfunction.
- Synonyms
- Cl2C10H5OH
Spectrophotometric Arginine Determination
2,4-Dichloro-1-naphthol has been utilised in modified Sakaguchi reactions for the spectrophotometric determination of arginine. This application is crucial in biochemical research for quantifying amino acid levels.
Urine Guanidino Compound Assays
The compound is employed in assays for guanidinoacetate and guanidinosuccinate in urine samples. These assays can provide insights into kidney function, as elevated levels may indicate dysfunction.
Organic Synthesis Intermediate
As a dichlorinated naphthol, it functions as a building block in the synthesis of more complex organic molecules. Its reactive sites allow for various chemical transformations.
| Molecular weight | 213.06 |
|---|---|
| Linear formula | Cl2C10H5OH |
| Assay | 95% |
| Solubility | pyridine: soluble5%, clear, colorless to dark yellow |
| Vapour density | 7.3 (vs air) |
| Application | 2,4-Dichloro-1-naphthol has been used in:• spectrophotometric determination of arginine with previous modifications of the Sakaguchi reaction1• guanidinoacetate and guanidinosuccinate assay of urine, an indicator of kidney dysfunction2 |
| Melting point | 104-107 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Dichloro-1-naphthol used for?
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2,4-Dichloro-1-naphthol is used in spectrophotometric determination of arginine and in assays for guanidinoacetate and guanidinosuccinate in urine, which can indicate kidney dysfunction. It also serves as a building block in organic synthesis.
What are the CAS number and chemical formula for 2,4-Dichloro-1-naphthol?
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The CAS number is 2050-76-2 and the linear chemical formula is Cl2C10H5OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Dichloro-1-naphthol with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,4-Dichloro-1-naphthol be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation to prevent respiratory irritation (H335). It is also a skin (H315) and eye (H319) irritant.
Is 2,4-Dichloro-1-naphthol available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents, including 2,4-Dichloro-1-naphthol.
How can I request a sample or quote for 2,4-Dichloro-1-naphthol?
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Please contact our sales team directly via the website or by phone to request a sample or obtain a quotation for 2,4-Dichloro-1-naphthol.
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