Boc-Dap(Fmoc)-OH
Boc-Dap(Fmoc)-OH (CAS: 122235-70-5) is a protected amino acid derivative with the molecular formula C23H26N2O6 and a molecular weight of 426.46 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and the development of unnatural amino acid derivatives. Its dual protection strategy allows for controlled stepwise elongation of peptide chains, making it a key intermediate in complex biochemical research and drug discovery.
- IUPAC
- Nα-Boc-Nβ-Fmoc-L-2,3-diaminopropionic acid,Boc-3-(Fmoc-amino)-L-alanine
- Synonyms
- Nα-Boc-Nβ-Fmoc-L-2,3-diaminopropionic acidBoc-3-(Fmoc-amino)-L-alanine
Peptide Synthesis
Boc-Dap(Fmoc)-OH is utilised as a protected amino acid in solid-phase and solution-phase peptide synthesis. The orthogonal Fmoc and Boc protecting groups enable selective deprotection and coupling reactions for constructing complex peptide sequences.
Unnatural Amino Acid Incorporation
This derivative facilitates the introduction of unnatural amino acids into peptides, expanding their structural diversity and functional properties. These modified peptides are crucial for probing biological mechanisms and developing novel therapeutics.
Chemical Biology Research
The compound is employed in chemical biology for creating modified peptides or peptidomimetics for studying protein-ligand interactions, enzyme activity, and cellular signalling pathways.
Organic Synthesis Intermediate
Beyond peptide chemistry, Boc-Dap(Fmoc)-OH functions as a versatile intermediate in multi-step organic syntheses requiring precisely functionalised diamine precursors.
| Molecular weight | 426.46 |
|---|---|
| Empirical formula | C23H26N2O6 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Dap(Fmoc)-OH used for?
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Boc-Dap(Fmoc)-OH is primarily used as a protected amino acid building block in peptide synthesis and for the incorporation of unnatural amino acids into peptides, finding applications in chemical biology research and organic synthesis.
What are the CAS number and molecular formula of Boc-Dap(Fmoc)-OH?
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The CAS number for Boc-Dap(Fmoc)-OH is 122235-70-5, and its molecular formula is C23H26N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Dap(Fmoc)-OH with a purity of ≥98.0% (HPLC). This product is intended for research and development purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
What safety precautions should be taken when handling Boc-Dap(Fmoc)-OH?
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When handling Boc-Dap(Fmoc)-OH, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. Respiratory protection, such as a type N95 (US) or type P1 (EN143) respirator filter, should be used. The compound is classified under WGK 3 in Germany, indicating a high hazard level.
Is Boc-Dap(Fmoc)-OH a controlled substance?
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The provided data does not indicate that Boc-Dap(Fmoc)-OH is a controlled substance.
How is Boc-Dap(Fmoc)-OH packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports fine chemicals with strict adherence to international regulations and quality standards to ensure product integrity and safety during transit.
How can I request a quote or sample of Boc-Dap(Fmoc)-OH?
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To request a quote or sample of Boc-Dap(Fmoc)-OH, please contact the Tech Serve Solutions sales team through our website or directly via email/phone.
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