Methyl 2-fluoropyridine-3-carboxylate
Methyl 2-fluoropyridine-3-carboxylate (CAS 446-26-4, C7H6FNO2) is a fluorinated heterocyclic building block with a molecular weight of 155.13 g/mol. This compound serves as a versatile intermediate in organic synthesis, particularly for the development of novel pharmaceutical agents and agrochemicals. Its pyridine core and fluorine substituent offer unique reactivity for constructing complex molecular architectures. Available from Tech Serve Solutions with an assay of 97%.
- IUPAC
- 2-Fluoronicotinic acid methyl ester
- Synonyms
- 2-Fluoronicotinic acid methyl ester

Pharmaceutical Synthesis
Utilised as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. The fluoropyridine motif is present in various therapeutic agents, contributing to altered metabolic stability and binding affinities.
Agrochemical Development
Employed in the research and development of new pesticides, herbicides, and fungicides. Fluorinated heterocycles often exhibit enhanced biological activity and improved environmental profiles.
Material Science Research
Can be incorporated into novel organic materials, leveraging its electronic and structural properties. Its use may contribute to the development of advanced functional materials.
Organic Synthesis Intermediate
Serves as a fundamental building block for introducing fluoropyridine moieties into diverse organic molecules. Its reactivity allows for various transformations in complex synthetic pathways.
| Molecular weight | 155.13 |
|---|---|
| Empirical formula | C7H6FNO2 |
| Assay | 97% |
| Boiling point | 75 °C/5 mmHg |
| Melting point | 22-26 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 2-fluoropyridine-3-carboxylate used for?
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Methyl 2-fluoropyridine-3-carboxylate (CAS 446-26-4) is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What are the CAS number and molecular formula?
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The CAS number is 446-26-4 and the molecular formula is C7H6FNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 2-fluoropyridine-3-carboxylate with a purity of 97% (assay). We do not represent this product as USP, BP, or EP grade.
How should Methyl 2-fluoropyridine-3-carboxylate be handled safely?
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Based on GHS classifications, this compound is a warning irritant (H315, H319, H335). It requires appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Handle in a well-ventilated area, and avoid dust formation.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents. We handle all aspects of shipping and international export, adhering to all necessary regulations.
How can I request a sample or a quote?
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To request a sample or a quote for Methyl 2-fluoropyridine-3-carboxylate, please contact our sales team through the website or by phone.
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