Boc-Glu-OPh
Boc-Glu-OPh (CAS 59587-94-9), also known as Boc-L-glutamic acid 1-phenyl ester, is a protected amino acid derivative with the molecular formula C16H21NO6. This compound serves as a valuable building block in peptide synthesis and related chemical research. Its structure allows for selective manipulation in complex organic synthesis pathways, making it a key intermediate in the development of novel biomolecules and pharmaceutical agents. The N-terminal Boc protection and C-terminal phenyl ester provide orthogonal protecting group strategies.
- IUPAC
- Boc-L-glutamic acid 1-phenyl ester
- Synonyms
- Boc-L-glutamic acid 1-phenyl ester
Peptide Synthesis
Boc-Glu-OPh is utilised as a protected amino acid in solid-phase and solution-phase peptide synthesis. The N-Boc group prevents unwanted reactions at the alpha-amino position, while the phenyl ester can be selectively cleaved under specific conditions.
Organic Synthesis
This compound acts as a versatile intermediate in the synthesis of complex organic molecules. Its functional groups can be modified or removed to introduce specific structural features required for target compounds.
Chemical Biology Research
Researchers in chemical biology may employ Boc-Glu-OPh for constructing labelled peptides or modified amino acid analogues to investigate biological processes at a molecular level.
Pharmaceutical Intermediate
It functions as a crucial building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), contributing to the development of new therapeutic agents.
| Molecular weight | 323.34 |
|---|---|
| Empirical formula | C16H21NO6 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Glu-OPh used for?
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Boc-Glu-OPh is primarily used as a protected amino acid derivative in peptide synthesis and as a versatile intermediate in general organic synthesis, including the development of pharmaceutical agents and in chemical biology research.
What is the CAS number and formula for Boc-Glu-OPh?
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The CAS number for Boc-Glu-OPh is 59587-94-9, and its empirical formula is C16H21NO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Glu-OPh with an assay of ≥98.0% (TLC). This is a research-grade material; we do not represent it as USP, BP, EP, or pharmacopoeia grade.
How should Boc-Glu-OPh be handled?
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Handling of Boc-Glu-OPh requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended if airborne exposure is possible. Note that it has a WGK Germany classification of 3.
Is Boc-Glu-OPh a controlled substance?
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The provided data does not indicate that Boc-Glu-OPh is a controlled substance.
How is Boc-Glu-OPh shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, capable of handling international shipments of Boc-Glu-OPh in compliance with all relevant regulations.
How can I request a sample or quote for Boc-Glu-OPh?
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To request a sample or quote for Boc-Glu-OPh, please contact our sales department via the website or by telephone, providing your specific requirements.
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