Boc-Gly-OH
Boc-Gly-OH (CAS: 4530-20-5), N-(tert-Butoxycarbonyl)glycine, is a vital protected amino acid derivative with a molecular weight of 175.18 g/mol. It plays a crucial role in organic synthesis and peptide chemistry as a building block. Its N-terminal Boc protecting group allows for selective manipulation during complex synthetic pathways, making it indispensable in research and development across various chemical disciplines.
- IUPAC
- N-(tert-Butoxycarbonyl)glycine,Boc-glycine
- Synonyms
- N-(tert-Butoxycarbonyl)glycineBoc-glycine

Peptide Synthesis
Boc-Gly-OH is a fundamental component in solid-phase and solution-phase peptide synthesis, enabling the controlled addition of glycine residues to growing peptide chains.
Organic Synthesis
It serves as a versatile synthon in complex organic molecule construction, where the protected amine functionality is required.
Chemical Biology Research
Used in the preparation of modified peptides and small molecules for investigating biological processes and drug discovery.
Pharmaceutical Intermediate
As a protected amino acid, it is employed in the multi-step synthesis of various pharmaceutical agents and active pharmaceutical ingredients (APIs).
| Molecular weight | 175.18 |
|---|---|
| Linear formula | (CH3)3COCONHCH2COOH |
| Assay | ≥99.0% (T) |
| Melting point | 86-89 °C(lit.)86-89 °C |
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Ignition residue | ≤0.05% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Gly-OH used for?
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Boc-Gly-OH is primarily used in peptide synthesis and as a building block in organic and chemical biology research, including the preparation of pharmaceutical intermediates.
What is the CAS number and formula for Boc-Gly-OH?
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The CAS number for Boc-Gly-OH is 4530-20-5, and its linear formula is (CH₃)₃COCONHCH₂COOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Gly-OH with an assay of ≥99.0% (T). This product is supplied for research and manufacturing use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the primary safety hazards associated with Boc-Gly-OH?
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Boc-Gly-OH is classified under UN 2811, Hazard Class 6.1 (Toxic substances), Packing Group III. Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, faceshields, and gloves, should be used during handling.
How is Boc-Gly-OH packed and shipped?
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Boc-Gly-OH is packed securely for export and shipped according to international regulations for hazardous materials. Please contact us for specific shipping and export details.
How can I request a quote or sample of Boc-Gly-OH?
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To request a quote or sample of Boc-Gly-OH, please contact our sales department through our website or by phone, providing your specific requirements.
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