Boc-Gly-OtBu
Boc-Gly-OtBu (CAS: 111652-20-1) is a tert-butyl ester of N-tert-butoxycarbonylglycine, with a molecular weight of 231.29 g/mol. This amino acid derivative is a valuable building block in organic synthesis, particularly in peptide chemistry and the construction of complex molecules. It facilitates controlled peptide bond formation and is widely utilised in research laboratories and chemical synthesis applications.
- IUPAC
- Boc-glycine tert-butyl ester
- Synonyms
- Boc-glycine tert-butyl ester

Peptide Synthesis
Boc-Gly-OtBu serves as a protected glycine residue for incorporating into peptide chains. Its tert-butoxycarbonyl (Boc) protecting group is stable under various reaction conditions and readily removed when required.
Organic Synthesis
This compound is a versatile intermediate in the synthesis of various organic molecules. It is employed in research and development for the creation of novel chemical entities.
Chemical Biology Research
Used as a tool compound in chemical biology for studying biological processes or developing new chemical probes, leveraging its specific structural features.
| Molecular weight | 231.29 |
|---|---|
| Linear formula | (CH3)3COC(O)NHCH2CO2C(CH3)3 |
| Assay | 99% |
| Melting point | 66-68 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-51 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Gly-OtBu used for?
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Boc-Gly-OtBu is primarily used as a protected building block in peptide synthesis and general organic synthesis for creating complex organic molecules and for research in chemical biology.
What is the CAS number and formula for Boc-Gly-OtBu?
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The CAS number for Boc-Gly-OtBu is 111652-20-1. Its linear formula is (CH3)3COC(O)NHCH2CO2C(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Gly-OtBu with a minimum purity of 99%. This product is suitable for research and general synthesis; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should Boc-Gly-OtBu be handled?
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Boc-Gly-OtBu is classified as harmful if swallowed (H302). Handle with appropriate personal protective equipment in a well-ventilated area to avoid ingestion and contact. Refer to the Safety Data Sheet for detailed handling instructions.
Is Boc-Gly-OtBu a controlled substance?
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The provided data does not indicate that Boc-Gly-OtBu is a controlled substance.
How is Boc-Gly-OtBu packed and shipped?
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Boc-Gly-OtBu is carefully packed to maintain its integrity during transit and is available for export worldwide by Tech Serve Solutions.
How can I request a sample or quote for Boc-Gly-OtBu?
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To request a sample or a quote for Boc-Gly-OtBu, please contact our sales department through the TSS website or by phone.
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