(R)-Xyl-SDP
(R)-Xyl-SDP (CAS: 917377-75-4), with the empirical formula C49H50P2 and a molecular weight of 700.87 g/mol, is a chiral phosphine ligand. It is widely recognised for its utility in asymmetric synthesis. This compound serves as a crucial component in catalysing enantioselective transformations, enabling the production of chiral molecules with high optical purity.
- IUPAC
- (R)-(+)-7,7′-Bis[di(3,5-dimethylphenyl)phosphino]-1,1′-spirobiindane,(R)-(+)-7,7′-Bis[di(3,5-dimethylphenyl)phosphino]-2,2′,3,3′-tetrahydro-1,1′-spirobiindene
Asymmetric Catalysis
(R)-Xyl-SDP is a privileged chiral ligand employed in various transition metal-catalysed asymmetric reactions. Its unique spirobiindane backbone imparts specific steric and electronic properties, facilitating high enantioselectivity in transformations such as hydrogenations, allylic alkylations, and cross-coupling reactions.
Chiral Ligand Synthesis
As a sophisticated phosphine ligand, (R)-Xyl-SDP is instrumental in the development of new catalytic systems. Its structure allows for fine-tuning of catalytic activity and selectivity, making it valuable in research for novel asymmetric methodologies.
Pharmaceutical Intermediate Synthesis
The ability of (R)-Xyl-SDP to promote enantioselective synthesis is critical in the production of chiral pharmaceutical intermediates. Access to enantiomerically pure building blocks is essential for the development of modern therapeutics.
| Molecular weight | 700.87 |
|---|---|
| Empirical formula | C49H50P2 |
| Optical activity | [α]22/D +64.0, c = 1 in chloroform |
| Storage temperature | −20°C |
| Melting point | >300 °C |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-Xyl-SDP used for?
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(R)-Xyl-SDP is primarily used as a chiral ligand in asymmetric catalysis for the synthesis of enantiomerically enriched compounds, particularly in the pharmaceutical and fine chemical industries.
What is the CAS number and chemical formula for (R)-Xyl-SDP?
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The CAS number for (R)-Xyl-SDP is 917377-75-4, and its empirical formula is C49H50P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-Xyl-SDP as a research-grade chemical. The purity and assay are specified on the Certificate of Analysis provided with each batch. TSS does not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards.
How should (R)-Xyl-SDP be handled and stored?
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Handle (R)-Xyl-SDP with appropriate personal protective equipment, including a dust mask (N95 recommended), eyeshields, and gloves, as it is classified as harmful if swallowed (H302). Store at -20°C to maintain its stability and efficacy.
Is (R)-Xyl-SDP a controlled substance?
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Based on the provided safety data, (R)-Xyl-SDP is not listed as a controlled substance. However, users should always verify local regulations.
How can I request a quote or sample for (R)-Xyl-SDP?
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To request a quote or a sample of (R)-Xyl-SDP, please contact the Tech Serve Solutions sales team through our website or by phone. Please specify the quantity required and your delivery location.
How is (R)-Xyl-SDP packed and exported?
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(R)-Xyl-SDP is carefully packaged to ensure stability during transit and is available for export globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
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