Boc-His(Trt)-OH
Nα-Boc-N(im)-trityl-L-histidine (CAS: 32926-43-5) is a protected amino acid derivative with the empirical formula C30H31N3O4 and a molecular weight of 497.58. It is essential in peptide synthesis, particularly for incorporating histidine residues while protecting the imidazole and alpha-amino groups. This compound finds utility in chemical biology and organic synthesis, serving as a building block for complex biomolecules and research chemicals.
- IUPAC
- Nα-Boc-N(im)-trityl-L-histidine
Peptide Synthesis
This N-protected and imidazole-protected histidine derivative is a crucial building block for solid-phase and solution-phase peptide synthesis. It allows for controlled coupling of histidine into peptide chains.
Chemical Biology
It serves as a valuable reagent in chemical biology for creating modified peptides or peptidomimetics. These molecules can be used to study biological processes or develop new therapeutic agents.
Organic Synthesis
The compound is employed in general organic synthesis for the construction of complex nitrogen-containing molecules. Its protected functional groups enable selective chemical transformations.
| Molecular weight | 497.58 |
|---|---|
| Empirical formula | C30H31N3O4 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D +12.5±1.0°, c = 1% in methanol |
| Melting point | ~130 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Boc-N(im)-trityl-L-histidine used for?
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Nα-Boc-N(im)-trityl-L-histidine is primarily used as a protected amino acid in peptide synthesis and as a building block in chemical biology and organic synthesis.
What is the CAS number and formula for Nα-Boc-N(im)-trityl-L-histidine?
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The CAS number is 32926-43-5 and the empirical formula is C30H31N3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nα-Boc-N(im)-trityl-L-histidine with a minimum purity of 98.0% as determined by TLC. This product is intended for research and technical use and is not represented as USP, BP, or EP grade.
How should Nα-Boc-N(im)-trityl-L-histidine be handled?
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Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Use a type N95 (US) or type P1 (EN143) respirator filter when handling. The material has a melting point of approximately 130 °C (dec.).
Is this chemical a controlled substance?
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The provided data does not indicate that Nα-Boc-N(im)-trityl-L-histidine (CAS: 32926-43-5) is a controlled substance.
How is this product packed and shipped?
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Tech Serve Solutions securely packs and exports fine chemicals globally. Please contact us for specific packaging and shipping details relevant to your location and order.
How can I request a sample or quote?
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To request a sample or a quotation for Nα-Boc-N(im)-trityl-L-histidine, please contact our sales team through the website or by phone.
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