Boc-Hyp-OH
Boc-Hyp-OH (CAS: 13726-69-7; Formula: C10H17NO5; MW: 231.25) is a N-protected hydroxyproline derivative used in peptide synthesis and chemical biology. This compound, trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline, is a valuable building block for constructing peptides with specific structural features and functionalities. Its applications span research and development in areas requiring modified amino acid incorporation.
- IUPAC
- trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline,Boc-L-hydroxyproline
- Synonyms
- trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-prolineBoc-L-hydroxyproline
Peptide Synthesis
Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis. Its tert-butoxycarbonyl (Boc) protecting group facilitates controlled chain elongation.
Chemical Biology Research
Incorporated into peptides to study protein structure-function relationships, enzyme inhibition, and biological pathways. The hydroxyproline moiety introduces specific conformational constraints.
Organic Synthesis
Utilised as a chiral auxiliary or intermediate in the synthesis of complex organic molecules, including pharmaceuticals and natural products.
Drug Discovery & Development
A key intermediate in the development of peptide-based therapeutics and peptidomimetics, enabling the creation of compounds with enhanced stability and bioavailability.
| Molecular weight | 231.25 |
|---|---|
| Empirical formula | C10H17NO5 |
| Assay | 97% |
| Optical activity | [α]20/D −78° in H2O |
| Melting point | 123-127 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Hyp-OH used for?
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Boc-Hyp-OH is primarily used as a protected amino acid derivative in peptide synthesis and for research in chemical biology and organic synthesis.
What is the CAS number and formula for Boc-Hyp-OH?
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The CAS number is 13726-69-7 and the empirical formula is C10H17NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Hyp-OH with an assay of 97%. This product is intended for research and laboratory use and is not represented as USP, BP, or EP grade.
How should Boc-Hyp-OH be handled safely?
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When handling Boc-Hyp-OH, it is essential to wear safety glasses and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if respiratory protection is required. Consult the Safety Data Sheet (SDS) for comprehensive handling information.
How is Boc-Hyp-OH packed, shipped, and exported?
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Boc-Hyp-OH is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions, a specialist supplier with extensive experience since 1998.
How can I request a sample or quote for Boc-Hyp-OH?
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To request a sample or obtain a quote for Boc-Hyp-OH, please visit the Tech Serve Solutions website or contact our sales department directly.
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