Boc-Ile-ONp
Boc-Ile-ONp, CAS 16948-38-2, with the molecular formula C17H24N2O6 and a molecular weight of 352.38 g/mol, is a key intermediate in peptide synthesis. It functions as a protected form of isoleucine, enabling controlled sequential addition of amino acids in peptide chain elongation. This compound is essential for researchers in chemical biology and peptide chemistry requiring precise control over peptide bond formation.
- IUPAC
- Boc-L-Isoleucine 4-nitrophenyl ester
- Synonyms
- Boc-L-Isoleucine 4-nitrophenyl ester

Peptide Synthesis
Boc-Ile-ONp serves as a crucial building block in solid-phase and solution-phase peptide synthesis. The Boc (tert-butyloxycarbonyl) protecting group allows for selective deprotection and coupling reactions.
Chemical Biology Research
This derivative is employed in constructing peptides for various biochemical studies, including protein structure-function analyses and the development of peptide-based therapeutics.
Organic Synthesis Intermediate
Beyond peptide chemistry, Boc-Ile-ONp can be utilised in complex organic synthesis pathways where protected isoleucine units are required.
| Molecular weight | 352.38 |
|---|---|
| Empirical formula | C17H24N2O6 |
| Assay | ≥98.0% (TLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Ile-ONp used for?
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Boc-Ile-ONp is primarily used as a protected amino acid derivative in peptide synthesis and for applications in chemical biology research.
What is the CAS number and molecular formula for Boc-Ile-ONp?
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The CAS number is 16948-38-2, and the molecular formula is C17H24N2O6.
What grade and purity does Tech Serve Solutions supply for Boc-Ile-ONp?
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Tech Serve Solutions supplies Boc-Ile-ONp with a purity of ≥98.0% as determined by TLC. This product is not classified as USP, BP, or EP grade.
How should Boc-Ile-ONp be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store at 2-8°C.
Does Tech Serve Solutions export Boc-Ile-ONp?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Boc-Ile-ONp.
How can I request a quote or sample of Boc-Ile-ONp?
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Please contact our sales team through the website to request a quote or a sample of Boc-Ile-ONp.
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