5-Trichloromethyl-4,5-dihydro-5-isoxazolol
5-Trichloromethyl-4,5-dihydro-5-isoxazolol (CAS: 34648-11-8) is a heterocyclic organic compound with the empirical formula C4H4Cl3NO2 and a molecular weight of 204.44 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly within the realm of heterocyclic chemistry. It is recognised for its utility in the creation of more complex molecular structures for research and development purposes.
- IUPAC
- 5-Hydroxy-5-trichloromethyl-4,5-dihydroisoxazole
- Synonyms
- 5-Hydroxy-5-trichloromethyl-4,5-dihydroisoxazole

Organic Synthesis Intermediate
This compound acts as a key intermediate in the synthesis of various organic molecules. Its structure allows for diverse chemical transformations, making it useful for constructing complex target compounds in research laboratories.
Heterocyclic Chemistry Research
As a dihydriisoxazole derivative, it is employed in studies focusing on heterocyclic chemistry. Researchers can utilise its functional groups to explore novel reaction pathways and develop new synthetic methodologies.
Building Block for Specialty Chemicals
The unique combination of a trichloromethyl group and an isoxazolol ring makes it a useful building block for the synthesis of specialty chemicals with potential applications in various fields.
| Molecular weight | 204.44 |
|---|---|
| Empirical formula | C4H4Cl3NO2 |
| Assay | ≥97.0%97.0-103.0% (T) |
| Melting point | 138-143 °C |


Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Trichloromethyl-4,5-dihydro-5-isoxazolol used for?
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5-Trichloromethyl-4,5-dihydro-5-isoxazolol is primarily used as a building block and intermediate in organic synthesis, particularly within heterocyclic chemistry research.
What is the CAS number and formula for this compound?
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The CAS number is 34648-11-8, and the empirical formula is C4H4Cl3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥97.0%, specified as 97.0-103.0% (T). This is typically considered a technical or research grade, and TSS does not represent it as USP, BP, or EP grade.
What are the main safety hazards associated with 5-Trichloromethyl-4,5-dihydro-5-isoxazolol?
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This compound is classified as Danger, with hazards including skin irritation (H315), serious eye damage (H318), and respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 or equivalent), should be used when handling.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions packs and exports this chemical in compliance with international shipping regulations for hazardous materials, ensuring safe transit to research institutions and industries worldwide.
How can I request a sample or quote for 5-Trichloromethyl-4,5-dihydro-5-isoxazolol?
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To request a sample or a quote, please contact our sales department via the website or by phone, providing your specific requirements and shipping details.
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