CP-226269
CP-226269 (CAS: 220941-93-5) is a fluorinated indole derivative with the molecular formula C18H19FN4 and a molecular weight of 310.37 g/mol. This compound presents as a light tan powder. It functions as a potent agonist, specifically recognised for its activity within dopaminergic pathways. CP-226269 is a valuable tool in neuroscientific research and the study of cell signalling, particularly concerning GPCR modulators and membrane protein biology.
- IUPAC
- 5-Fluoro-2-{[4-(2-pyridinyl)-1-piperazinyl]methyl}-1H-indole

Neuroscience Research
Utilised as a dopaminergic agonist, CP-226269 is instrumental in studying neurotransmission and its role in neurological processes. Its activity makes it a key compound for research into conditions affecting the central nervous system.
GPCR Modulation Studies
This compound serves as a valuable tool for investigating G protein-coupled receptors (GPCRs) and their signalling cascades. Researchers employ it to understand the complex mechanisms of GPCR proteins and explore potential therapeutic targets.
Cell Signalling Investigations
CP-226269 aids in the elucidation of cell signalling pathways, particularly those involving dopaminergic systems and membrane protein interactions. It is a useful biochemical reagent for in vitro studies.
Drug Discovery and Development
As an approved therapeutic/drug candidate and a bioactive small molecule, CP-226269 is of interest in preclinical research for developing novel therapeutics. Its well-defined activity profile supports its use in early-stage drug discovery.
| Molecular weight | 310.37 |
|---|---|
| Empirical formula | C18H19FN4 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | light tan |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | −20°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is CP-226269 primarily used for?
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CP-226269 is primarily used in neuroscience research as a dopaminergic agonist to study neurotransmission, cell signalling pathways, and G protein-coupled receptor (GPCR) modulation. It is also considered a drug candidate for therapeutic development.
What are the CAS number and molecular formula for CP-226269?
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The CAS number for CP-226269 is 220941-93-5, and its empirical formula is C18H19FN4.
What grade and purity does Tech Serve Solutions supply for CP-226269?
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Tech Serve Solutions supplies CP-226269 with a purity of ≥98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, or EP grade.
What are the safety considerations for handling CP-226269?
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Refer to the Safety Data Sheet (SDS) for detailed hazard information. Handle with appropriate personal protective equipment (PPE) in a well-ventilated area. Store at -20°C.
How is CP-226269 supplied and exported?
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CP-226269 is supplied as a light tan powder and is typically stored at -20°C. Tech Serve Solutions is a global supplier and exporter of fine chemicals, and we can accommodate various shipping and export requirements.
How can I request a sample or quote for CP-226269?
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To request a sample or quote for CP-226269, please contact our sales department via the website or direct email, providing your specific requirements and shipping details.
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