Boc-4-Abz-OH
Boc-4-Abz-OH (CAS: 66493-39-8) is a protected aromatic amino acid derivative with the linear formula (CH3)3CO2CNHC6H4CO2H and a molecular weight of 237.25 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology. Its structure facilitates specific modifications and coupling reactions essential for creating complex molecules and research compounds.
- IUPAC
- 4-(Boc-amino)benzoic acid
- Synonyms
- 4-(Boc-amino)benzoic acid

Peptide Synthesis
Boc-4-Abz-OH is utilised as a protected amino acid in solid-phase and solution-phase peptide synthesis. The Boc (tert-butyloxycarbonyl) protecting group allows for controlled coupling reactions, enabling the sequential assembly of peptide chains.
Chemical Biology Research
This derivative finds application in chemical biology for the development of modified peptides, probes, and biomolecules. Its structure can be incorporated to study protein function, enzyme interactions, or to create novel biological agents.
Organic Synthesis Intermediate
As an unnatural amino acid derivative, Boc-4-Abz-OH is employed as an intermediate in complex organic synthesis pathways. It enables the introduction of specific structural motifs into target molecules.
| Molecular weight | 237.25 |
|---|---|
| Linear formula | (CH3)3CO2CNHC6H4CO2H |
| Assay | ≥98.0% (T) |
| Melting point | ~200 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-4-Abz-OH primarily used for?
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Boc-4-Abz-OH is primarily used as a protected building block in peptide synthesis, chemical biology research, and as an intermediate in organic synthesis.
What is the CAS number and formula for Boc-4-Abz-OH?
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The CAS number for Boc-4-Abz-OH is 66493-39-8, and its linear formula is (CH3)3CO2CNHC6H4CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-4-Abz-OH with an assay of ≥98.0% (T). This is a research grade material; TSS does not represent it as USP, BP, or EP grade.
What are the key safety considerations when handling Boc-4-Abz-OH?
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When handling Boc-4-Abz-OH, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The compound is classified under WGK Germany 3.
How is Boc-4-Abz-OH typically packed and exported?
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Boc-4-Abz-OH is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Boc-4-Abz-OH?
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To request a sample or a quotation for Boc-4-Abz-OH, please contact our sales team through the website or via direct inquiry.
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