Boc-4-azido-Phe-OH
N-Boc-4-azido-L-phenylalanine (CAS: 33173-55-6) is a protected unnatural amino acid derivative with the molecular formula C14H18N4O4. This compound serves as a valuable chiral building block in organic synthesis and peptide chemistry. Its azide functionality allows for click chemistry reactions, making it useful in chemical biology and conjugation chemistry for labeling and modifying biomolecules.
- IUPAC
- N-Boc-4-azido-L-phenylalanine
- Synonyms
- N-Boc-4-azido-L-phenylalanine
Chemical Biology & Bioconjugation
The azide group enables the incorporation of N-Boc-4-azido-L-phenylalanine into peptides and proteins via click chemistry. This facilitates bioorthogonal labeling, allowing for the study of biological processes or the development of targeted therapeutics.
Peptide Synthesis
As a protected unnatural amino acid, it can be incorporated into peptide sequences to create peptidomimetics or peptides with novel properties. The Boc protection offers standard amine protection strategy in solid-phase or solution-phase peptide synthesis.
Asymmetric Synthesis
The inherent chirality of this phenylalanine derivative makes it a useful chiral building block for the synthesis of complex organic molecules where stereochemical control is paramount.
Organic Synthesis
This compound is a versatile reagent in organic synthesis, offering a unique combination of a protected amino acid and a reactive azide moiety for diverse synthetic transformations.
| Molecular weight | 306.32 |
|---|---|
| Empirical formula | C14H18N4O4 |
| Assay | ≥95% (HPLC) |
| Optical activity | [α]/D 48.0±3.0°, c = 1 in chloroform |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-4-azido-L-phenylalanine used for?
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N-Boc-4-azido-L-phenylalanine is primarily used in chemical biology for bioconjugation via click chemistry, in peptide synthesis to create modified peptides, and as a chiral building block in asymmetric organic synthesis.
What is the CAS number and formula for N-Boc-4-azido-L-phenylalanine?
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The CAS number is 33173-55-6 and the empirical formula is C14H18N4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-4-azido-L-phenylalanine with an assay of ≥95% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for this chemical?
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This compound is a Warning (GHS07) substance, causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation.
How is N-Boc-4-azido-L-phenylalanine shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. We handle all aspects of shipping and export documentation in compliance with international regulations.
How can I request a sample or quote for N-Boc-4-azido-L-phenylalanine?
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Please contact our sales team via the website or direct email to request a sample or a quotation for N-Boc-4-azido-L-phenylalanine.
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