Boc-4,5-dehydro-Leu-OH (dicyclohexylammonium) salt
Boc-4,5-dehydro-L-leucine (dicyclohexylammonium) salt, identified by CAS number 87720-54-5, is a derivative of leucine with a molecular weight of 410.59. This compound serves as a valuable building block in organic synthesis, particularly within peptide chemistry and the development of unnatural amino acids. Its protected amino group and unsaturated side chain offer unique reactivity for constructing complex molecules and exploring novel chemical structures. Supplied by TSS for research and synthesis purposes.
- IUPAC
- (S)-2-(Boc-amino)-4-methyl-4-pentenoic acid (dicyclohexylammonium) salt,Boc-4,5-dehydro-L-leucine (dicyclohexylammonium) salt
- Synonyms
- (S)-2-(Boc-amino)-4-methyl-4-pentenoic acid (dicyclohexylammonium) saltBoc-4,5-dehydro-L-leucine dicyclohexylammonium salt
Peptide Synthesis
Used as a modified amino acid precursor in the solid-phase or solution-phase synthesis of peptides. The Boc protecting group allows for selective deprotection during chain elongation, while the dehydro-amino acid moiety can introduce specific conformational constraints or serve as a handle for further chemical modification.
Unnatural Amino Acid Development
Incorporated into peptide sequences to create peptidomimetics or peptides with enhanced stability, altered biological activity, or novel structural features. This dehydro-amino acid derivative is instrumental in expanding the chemical space accessible to peptide-based therapeutics and research tools.
Chemical Biology Research
Enables the synthesis of custom peptides and conjugates for studying protein-ligand interactions, enzyme mechanisms, and biological pathways. Its unique structure can be leveraged to probe specific biological targets or to develop molecular probes.
Organic Synthesis Intermediate
Acts as a versatile intermediate in the synthesis of complex organic molecules beyond peptides. The reactive double bond and the protected amine offer opportunities for various synthetic transformations.
| Molecular weight | 410.59 |
|---|---|
| Empirical formula | C11H19NO4·C12H23N |
| Assay | ≥96.0% (HPLC) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-37/38-41-50/53 |
| Safety statements (S) | 26-39-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-4,5-dehydro-L-leucine (dicyclohexylammonium) salt used for?
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Boc-4,5-dehydro-L-leucine (dicyclohexylammonium) salt is primarily used in peptide synthesis, the development of unnatural amino acids, chemical biology research, and as a versatile intermediate in organic synthesis. It allows for the creation of modified peptides and complex organic structures.
What is the CAS number and formula for this compound?
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The CAS number is 87720-54-5 and the empirical formula is C11H19NO4·C12H23N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-4,5-dehydro-L-leucine (dicyclohexylammonium) salt with an assay of ≥96.0% determined by HPLC. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Boc-4,5-dehydro-L-leucine (dicyclohexylammonium) salt be handled?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. This compound is corrosive and may cause serious eye damage, skin irritation, and respiratory irritation. It is also harmful if swallowed and toxic to aquatic life with long-lasting effects. Ensure adequate ventilation and follow all safety guidelines.
How is this chemical packed and exported?
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Boc-4,5-dehydro-L-leucine (dicyclohexylammonium) salt is packed according to industry standards for safe transport and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations, including UN 3077 (9 / PGIII).
How can I request a sample or quote?
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To request a sample or a quotation for Boc-4,5-dehydro-L-leucine (dicyclohexylammonium) salt, please contact our sales team through the TSS website or by calling our direct line. Specify the quantity required and your delivery details.
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