Boc-4-phenyl-Phe-OH
Boc-4-phenyl-Phe-OH (CAS 147923-08-8) is a protected amino acid derivative, specifically N-tert-butoxycarbonyl-4-phenyl-L-phenylalanine. With a molecular weight of 341.40 g/mol, this compound serves as a valuable building block in peptide synthesis and organic chemistry. Its structure, featuring a Boc-protected amine and a biphenyl moiety, makes it suitable for introducing modified phenylalanine residues into peptides and for applications in chemical biology and synthesis.
- IUPAC
- (S)-2-(Boc-amino)-3-(4-biphenylyl)propionic acid,Boc-4-phenyl-L-phenylalanine,Boc-Bip-OH
- Synonyms
- (S)-2-(Boc-amino)-3-(4-biphenylyl)propionic acidBoc-4-phenyl-L-phenylalanineBoc-Bip-OH
![Boc-4-phenyl-Phe-OH (C6H5C6H4CH2CH[NHCO2C(CH3)3]CO2H) — chemical structure, CAS 147923-08-8; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F147923-08-8.png&w=3840&q=75)
Peptide Synthesis
Boc-4-phenyl-Phe-OH is utilised as a protected amino acid in solid-phase and solution-phase peptide synthesis. It allows for the controlled incorporation of non-canonical phenylalanine residues with a biphenyl side chain into peptide sequences.
Chemical Biology
This compound can be employed in chemical biology research to create modified peptides or peptidomimetics with altered pharmacological or structural properties. The biphenyl group can influence molecular interactions and biological activity.
Organic Synthesis
As a versatile building block, Boc-4-phenyl-Phe-OH finds application in complex organic synthesis routes. Its protected functional groups enable selective transformations in the development of novel molecular architectures.
| Molecular weight | 341.40 |
|---|---|
| Linear formula | C6H5C6H4CH2CH[NHCO2C(CH3)3]CO2H |
| Assay | 97% |
| Optical activity | [α]22/D +21°, c = 2 in methanol |
| Melting point | 103-107 °C(lit.) |
Hazard statements
- H361D
Precautionary statements
- P281Use personal protective equipment as required
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-4-phenyl-Phe-OH used for?
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Boc-4-phenyl-Phe-OH is primarily used as a protected amino acid building block in peptide synthesis, chemical biology research, and general organic synthesis.
What is the CAS number and chemical formula for Boc-4-phenyl-Phe-OH?
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The CAS number for Boc-4-phenyl-Phe-OH is 147923-08-8. Its linear formula is C6H5C6H4CH2CH[NHCO2C(CH3)3]CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-4-phenyl-Phe-OH with an assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should Boc-4-phenyl-Phe-OH be handled?
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Boc-4-phenyl-Phe-OH is classified with GHS08 and carries a Warning signal word. It has the hazard statement H361d (Suspected of damaging fertility or the unborn child). Handle with appropriate personal protective equipment (P281) in a well-ventilated area.
Is Boc-4-phenyl-Phe-OH a controlled substance?
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The provided data does not indicate that Boc-4-phenyl-Phe-OH is a controlled substance.
How is Boc-4-phenyl-Phe-OH typically shipped and exported?
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Tech Serve Solutions, as a global supplier and exporter, ships and exports chemicals including Boc-4-phenyl-Phe-OH in compliance with international regulations for the safe transport of chemical goods.
How can I request a sample or quote for Boc-4-phenyl-Phe-OH?
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To request a sample or obtain a quote for Boc-4-phenyl-Phe-OH, please contact the Tech Serve Solutions sales team through the website or by phone.
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