Boc-4-tert-butyl-D-Phe-OH
Boc-4-tert-butyl-D-Phe-OH (CAS 250611-12-2), with the molecular formula C18H27NO4 and a molecular weight of 321.41 g/mol, is a protected unnatural amino acid derivative. It features a tert-butyl group at the para position of the phenyl ring and is protected with a Boc group on the amine. This compound is primarily utilised in chemical synthesis and peptide chemistry, serving as a building block for complex molecules.
- IUPAC
- Boc-4-tert-butyl-D-phenylalanine

Peptide Synthesis
As a Boc-protected unnatural amino acid, Boc-4-tert-butyl-D-Phe-OH is valuable for introducing specific structural modifications into peptides. It enables the creation of peptides with altered pharmacological or biological properties.
Chemical Synthesis
This compound serves as a chiral building block in organic synthesis. Its unique structure, featuring both a tert-butyl substituent and a D-phenylalanine backbone, allows for the construction of complex molecular architectures.
Chemical Biology Research
The incorporation of unnatural amino acids like Boc-4-tert-butyl-D-Phe-OH can be used to probe biological systems. Researchers utilise such derivatives to study protein function, drug interactions, and molecular recognition.
| Molecular weight | 321.41 |
|---|---|
| Empirical formula | C18H27NO4 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-4-tert-butyl-D-Phe-OH used for?
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Boc-4-tert-butyl-D-Phe-OH is used in peptide synthesis, chemical synthesis, and chemical biology research as a protected unnatural amino acid building block.
What are the CAS number and formula for Boc-4-tert-butyl-D-Phe-OH?
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The CAS number is 250611-12-2 and the empirical formula is C18H27NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-4-tert-butyl-D-Phe-OH with an assay of ≥98.0% (HPLC). This is a research grade material and TSS does not represent it as USP, BP, or EP.
How should Boc-4-tert-butyl-D-Phe-OH be handled?
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Handle Boc-4-tert-butyl-D-Phe-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a WGK Germany rating of 3.
Does Tech Serve Solutions export Boc-4-tert-butyl-D-Phe-OH?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a quote or sample for Boc-4-tert-butyl-D-Phe-OH?
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Please contact our sales team via the website to request a quote or a sample for Boc-4-tert-butyl-D-Phe-OH.
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