Boc-4-tert-butyl-Phe-OH
Boc-4-tert-butyl-L-phenylalanine (CAS: 143415-62-7) is a protected unnatural amino acid derivative with the molecular formula C18H27NO4 and a molecular weight of 321.41 g/mol. It plays a significant role as a building block in complex organic synthesis, particularly within peptide chemistry. Its structure allows for controlled peptide chain elongation, making it valuable for creating novel peptides with tailored properties for research and development.
- IUPAC
- Boc-4-tert-butyl-L-phenylalanine

Peptide Synthesis
Serves as a protected unnatural amino acid for incorporating tert-butyl phenylalanine residues into peptide sequences. This modification can influence peptide structure, stability, and biological activity.
Chemical Synthesis
A versatile intermediate in the synthesis of complex organic molecules. The Boc protecting group allows for selective reactions and deprotection strategies in multi-step syntheses.
Chemical Biology Research
Utilised in the design and synthesis of modified peptides for studying protein-ligand interactions, enzyme mechanisms, and other biological processes.
Unnatural Amino Acid Research
Essential for researchers exploring the incorporation and utility of non-proteinogenic amino acids in novel peptide and protein structures.
| Molecular weight | 321.41 |
|---|---|
| Empirical formula | C18H27NO4 |
| Assay | ≥98.0% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-4-tert-butyl-L-phenylalanine used for?
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Boc-4-tert-butyl-L-phenylalanine is primarily used as a protected building block in peptide synthesis and as an intermediate in general chemical synthesis, particularly for creating unnatural amino acid derivatives for research.
What are the CAS number and molecular formula?
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The CAS number for Boc-4-tert-butyl-L-phenylalanine is 143415-62-7, and its molecular formula is C18H27NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-4-tert-butyl-L-phenylalanine with an assay of ≥98.0%. It is supplied for research purposes and not represented as USP, BP, EP, or other pharmacopoeial grades.
How should Boc-4-tert-butyl-L-phenylalanine be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Dispose of this material and its container in accordance with local regulations. It has a WGK Germany classification of 3.
Is this chemical packed and shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Boc-4-tert-butyl-L-phenylalanine, adhering to all relevant shipping regulations.
How can I request a sample or a quote?
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To request a sample or obtain a quote for Boc-4-tert-butyl-L-phenylalanine, please contact our sales team through the website or direct inquiry channels.
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