Imiquimod
Imiquimod (CAS: 99011-02-6, Formula: C14H16N4, MW: 240.30) is a synthetic small molecule with immunostimulatory properties. It functions as a Toll-like receptor 7 (TLR7) agonist, activating the innate and adaptive immune systems. This compound is primarily utilised in scientific research for studying immune responses, cellular signalling pathways, and as a potential agent in oncology and immunology research. Available as a solid with an assay of ≥98% (HPLC).
- IUPAC
- 1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
Immunology Research
Imiquimod serves as a valuable tool in immunology research for its ability to activate Toll-like receptor 7 (TLR7). This activation triggers downstream signalling pathways, leading to the production of various cytokines and chemokines, making it useful for studying innate and adaptive immune responses.
Oncology Studies
As an immune response modifier, Imiquimod is explored in preclinical oncology research. Its capacity to stimulate the immune system to target and eliminate cancer cells makes it a subject of interest for developing novel cancer therapies.
Cellular Signalling Research
The compound's mechanism of action, involving TLR7 agonism, makes it an important research chemical for investigating cellular signalling pathways related to immune activation and inflammation. This aids in understanding complex biological processes.
| Molecular weight | 240.30 |
|---|---|
| Empirical formula | C14H16N4 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Solubility | H2O: DMSO: soluble4 mg/mL (warming to 60 °C for 15 minutes) |
Hazard statements
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Imiquimod used for?
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Imiquimod is used in scientific research, particularly in immunology and oncology studies, for its immunostimulatory properties mediated through Toll-like receptor 7 (TLR7) agonism. It is a valuable tool for investigating immune responses and cellular signalling.
What is the CAS number and chemical formula for Imiquimod?
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The CAS number for Imiquimod is 99011-02-6, and its chemical formula is C14H16N4.
What grade and purity does Tech Serve Solutions supply for Imiquimod?
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Tech Serve Solutions supplies Imiquimod with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should I handle Imiquimod safely?
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Imiquimod is classified as acutely toxic if swallowed, causes skin irritation, serious eye irritation, and may cause respiratory irritation (H300-H315-H319-H335). When handling, use appropriate personal protective equipment including eyeshields, face shields, gloves, and a P2 respirator. Ensure adequate ventilation.
Is Imiquimod a controlled substance?
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The provided data does not indicate that Imiquimod is a controlled substance. However, users should always verify relevant local regulations.
How is Imiquimod packed and shipped?
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Imiquimod is typically supplied as a solid. For international shipment, it is classified under UN 2811, Hazard Class 6.1, Packing Group III, indicating it is a toxic solid, organic, n.o.s. (Imiquimod).
How can I request a sample or quote for Imiquimod?
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To request a sample or obtain a quote for Imiquimod, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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