3-Chloro-5-fluorobenzonitrile
3-Chloro-5-fluorobenzonitrile (CAS: 327056-73-5) is a fluorinated aromatic organic compound with the formula ClC6H3(F)CN and a molecular weight of 155.56 g/mol. This nitrile serves as a versatile building block in organic synthesis, particularly in the development of complex molecules for research and pharmaceutical applications. Its structure, featuring both a chlorine and a fluorine atom on the benzene ring along with a nitrile group, offers distinct reactivity for various chemical transformations.

Organic Synthesis Intermediate
Utilised as a key intermediate in the multi-step synthesis of complex organic molecules. Its functional groups allow for diverse chemical reactions, making it valuable in research and development settings.
Pharmaceutical Research
A valuable building block for medicinal chemists engaged in the discovery and development of novel pharmaceutical agents. Its specific structural features can be incorporated into potential drug candidates.
Agrochemical Development
Employed in the synthesis pathways for new agrochemical compounds. The presence of fluorine can influence the biological activity and persistence of target molecules.
Materials Science
Can be incorporated into the synthesis of specialised polymers or organic materials where its unique electronic or physical properties are beneficial.
| Molecular weight | 155.56 |
|---|---|
| Linear formula | ClC6H3(F)CN |
| Assay | 97% |
| Melting point | 54-59 °C(lit.) |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 89 °C / 192.2 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-5-fluorobenzonitrile used for?
+
3-Chloro-5-fluorobenzonitrile is primarily used as a building block and intermediate in organic synthesis, particularly for pharmaceutical research and the development of agrochemicals and specialised materials.
What is the CAS number and formula for 3-Chloro-5-fluorobenzonitrile?
+
The CAS number is 327056-73-5 and the molecular formula is ClC6H3(F)CN.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-Chloro-5-fluorobenzonitrile with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should 3-Chloro-5-fluorobenzonitrile be handled?
+
Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It is classified as a Warning substance with hazard statement H319 (Causes serious eye irritation).
How is 3-Chloro-5-fluorobenzonitrile exported and shipped?
+
As a global supplier and exporter, Tech Serve Solutions ships fine chemicals worldwide, adhering to all relevant transportation and export regulations.
How can I request a quote or sample for 3-Chloro-5-fluorobenzonitrile?
+
Please contact our sales team via the website or listed phone number to request a quote or a sample for 3-Chloro-5-fluorobenzonitrile.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis