3-Chloro-5-fluorosalicylaldehyde

CAS 82128-69-6ClC6H2(F)(OH)CHOChemical Synthesis

3-Chloro-5-fluorosalicylaldehyde (CAS: 82128-69-6) is a fluorinated aromatic aldehyde with the molecular formula ClC6H2(F)(OH)CHO and a molecular weight of 174.56 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for the introduction of fluorinated moieties into more complex molecular structures. Its reactivity makes it suitable for diverse chemical transformations in research and development settings.

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3-Chloro-5-fluorosalicylaldehyde (ClC6H2(F)(OH)CHO) — chemical structure, CAS 82128-69-6; Chemistry, fine chemical supplied by Tech Serve Solutions

AldehydesBuilding BlocksCarbonyl CompoundsChemical SynthesisFluorinated Building BlocksOrganic Building Blocks

01 /Applications

Chemical Synthesis Intermediate

Utilised as a key intermediate in the multi-step synthesis of fine chemicals and active pharmaceutical ingredients. Its aldehyde and phenolic hydroxyl groups offer versatile reaction sites for further functionalisation.

Fluorinated Compound Development

Essential for researchers developing novel fluorinated organic compounds, leveraging its incorporated fluorine atom for altered physical and biological properties.

Research and Development Reagent

A critical reagent in academic and industrial research laboratories for exploring new synthetic pathways and developing advanced materials.

02 /Properties

Molecular weight	174.56
Linear formula	ClC6H2(F)(OH)CHO
Assay	97%
Melting point	95-99 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H300Fatal if swallowed
H318Causes serious eye damage

Precautionary statements

P264Wash thoroughly after handling
P280Wear protective gloves, clothing and eye/face protection
P301IF SWALLOWED
P305IF IN EYES

Protective equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25-41
Safety statements (S)	26-36/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

82128-69-6

MDL number

MFCD04039291

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-Chloro-5-fluorosalicylaldehyde used for?

3-Chloro-5-fluorosalicylaldehyde is primarily used as a building block and intermediate in organic synthesis, particularly for creating fluorinated organic compounds in research and development.

What is the CAS number and chemical formula for 3-Chloro-5-fluorosalicylaldehyde?

The CAS number is 82128-69-6 and the chemical formula is ClC6H2(F)(OH)CHO.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 3-Chloro-5-fluorosalicylaldehyde with an assay of 97%. This is a technical grade, and TSS does not represent it as USP, BP, or EP grade.

How should 3-Chloro-5-fluorosalicylaldehyde be handled safely?

This compound is classified as Danger, with hazards H300 (Fatal if swallowed) and H318 (Causes serious eye damage). Handle with appropriate personal protective equipment including eyeshields, face shields, gloves, and a P2 respirator cartridge. In case of eye contact, rinse cautiously with water for several minutes and seek immediate medical attention.