3-Chloro-5-fluoroanisole
3-Chloro-5-fluoroanisole (CAS: 202925-08-4), with the molecular formula ClC6H3(F)OCH3 and a molar mass of 160.57 g/mol, is a specialised fluorinated aromatic compound. It serves as a valuable building block in organic synthesis, particularly for introducing substituted anisole moieties. Its utility spans the development of complex molecules within the pharmaceutical and agrochemical industries, and in materials science research.

Pharmaceutical Intermediate
Utilised as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), contributing to the development of novel therapeutics.
Agrochemical Development
Serves as a building block for the creation of new crop protection agents and pesticides, aiding in agricultural innovation.
Materials Science
Employed in the research and development of advanced materials where specific fluorinated aromatic structures are required.
Organic Synthesis Reagent
A versatile reagent for introducing a chloro-fluoro-anisole functional group into diverse organic molecules during multi-step syntheses.
| Molecular weight | 160.57 |
|---|---|
| Linear formula | ClC6H3(F)OCH3 |
| Assay | 97% |
| Boiling point | 189 °C(lit.) |
| Density | 1.265 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.511(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-5-fluoroanisole used for?
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3-Chloro-5-fluoroanisole is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and chemical formula for 3-Chloro-5-fluoroanisole?
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The CAS number is 202925-08-4, and its chemical formula is ClC6H3(F)OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloro-5-fluoroanisole with a minimum purity of 97%. This product is intended for research and chemical synthesis and is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the main safety hazards associated with 3-Chloro-5-fluoroanisole?
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3-Chloro-5-fluoroanisole is classified with GHS07 (Warning) and carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Refer to the safety data sheet for comprehensive handling information.
How is 3-Chloro-5-fluoroanisole packed and shipped?
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3-Chloro-5-fluoroanisole is packed and shipped according to relevant safety and transport regulations, suitable for global export.
How can I request a quote or sample for 3-Chloro-5-fluoroanisole?
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Please contact our sales department or use the online enquiry form on our website to request a quote or a sample of 3-Chloro-5-fluoroanisole.
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