3-Chloro-5-(trifluoromethyl)pyridine
3-Chloro-5-(trifluoromethyl)pyridine (CAS: 85148-26-1), with the molecular formula C6H3ClF3N and a molecular weight of 181.54 g/mol, is a halogenated pyridine derivative. This compound serves as a valuable building block in organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its specific structure allows for targeted chemical modifications, facilitating the development of novel active ingredients and complex molecular architectures.

Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs), leveraging its pyridine core and trifluoromethyl substituent for the development of new therapeutic agents.
Agrochemical Synthesis
Acts as a key intermediate in the production of crop protection chemicals, including herbicides and insecticides, where the trifluoromethylpyridine moiety imparts desirable properties.
Material Science Research
Employed in the development of functional materials where halogenated heterocyclic structures are required for specific electronic or physical characteristics.
Organic Synthesis Building Block
A versatile reagent for introducing the 3-chloro-5-(trifluoromethyl)pyridinyl group into various organic molecules via established synthetic methodologies.
| Molecular weight | 181.54 |
|---|---|
| Empirical formula | C6H3ClF3N |
| Assay | 97% |
| Boiling point | 133-138 °C |
| Melting point | 23-27 °C |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Flash point | 54 °C / 129.2 °F |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-5-(trifluoromethyl)pyridine used for?
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3-Chloro-5-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis for the development of pharmaceuticals, agrochemicals, and functional materials.
What is the CAS number and formula for 3-Chloro-5-(trifluoromethyl)pyridine?
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The CAS number is 85148-26-1 and the empirical formula is C6H3ClF3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloro-5-(trifluoromethyl)pyridine with a minimum purity of 97% (assay). This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, or EP grade.
How should 3-Chloro-5-(trifluoromethyl)pyridine be handled?
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This compound is classified as Danger, with hazards including toxicity if swallowed and skin, eye, and respiratory irritation (H301-H315-H319-H335). Handle with appropriate personal protective equipment in a well-ventilated area, following strict laboratory safety protocols.
Is 3-Chloro-5-(trifluoromethyl)pyridine a controlled substance?
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The provided data does not indicate that 3-Chloro-5-(trifluoromethyl)pyridine is a controlled substance. However, customers should always verify compliance with local regulations.
How is 3-Chloro-5-(trifluoromethyl)pyridine packed and exported?
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3-Chloro-5-(trifluoromethyl)pyridine is packed according to UN 2811 6.1 / PGIII regulations for hazardous materials. Tech Serve Solutions is a global supplier and exporter, capable of shipping this chemical worldwide.
How can I request a quote or sample for 3-Chloro-5-(trifluoromethyl)pyridine?
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To request a quote or sample of 3-Chloro-5-(trifluoromethyl)pyridine, please contact our sales team through the website or by phone, providing your required quantity and shipping details.
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